{"title":"Give me a sign(ature): Converging on the CSC of glioblastoma.","authors":"Kunal S Patel, Lindsey Dudley, Harley I Kornblum","doi":"10.1016/j.neuron.2024.11.012","DOIUrl":null,"url":null,"abstract":"<p><p>The identification of stem cells in glioblastomas has been controversial. In this issue of Neuron, Xie et al.<sup>1</sup> establish gene signatures for cellular states and a quiescent cancer stem cell (qCSC) and demonstrate that the qCSC population expands in recurrence.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"112 24","pages":"3987-3988"},"PeriodicalIF":14.7000,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2024.11.012","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The identification of stem cells in glioblastomas has been controversial. In this issue of Neuron, Xie et al.1 establish gene signatures for cellular states and a quiescent cancer stem cell (qCSC) and demonstrate that the qCSC population expands in recurrence.
期刊介绍:
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.