Reassessing the Significance of Mycobacterium in Neglected Tropical Diseases: A Study Protocol in Nigeria.

IF 1.6 Q4 INFECTIOUS DISEASES
International Journal of Mycobacteriology Pub Date : 2024-10-01 Epub Date: 2024-12-19 DOI:10.4103/ijmy.ijmy_145_24
Ngozi Ekeke, Francis Sunday Iyama, Edmund Ndudi Ossai, Joseph Ngozi Chukwu, Chinwe Chika Eze, Daniel Egbule, Charles Nwafor, Martin I Njoku, Anthony O Meka, Michael Odama, Okechukwu E Ezeakile, Ngozi N Murphy-Okpala
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引用次数: 0

Abstract

Background: Neglected tropical diseases (NTDs) significantly impact the physical and mental well-being of affected individuals, particularly in Nigeria. This study aims to evaluate the effectiveness of integrating mental health services with self-care practices for individuals suffering from leprosy, Buruli ulcer (BU), and lymphatic filariasis (LF). The role of trained Healthcare Workers (HCWs) and NTD champions (NTD-Cs) will be explored to enhance health outcomes in this population.

Methods: A cluster-randomized controlled trial was conducted in four local government areas (clusters) with the highest incidence of leprosy, BU, or LF. Clusters were purposively selected and randomized into intervention and control groups: three clusters received interventions, while one served as a control. The intervention arms include (a) Mental health and self-care interventions by NTD-Cs. (b) Mental health and self-care interventions by HCWs. (c) Self-care interventions only by HCWs. d) Control group receiving standard care. Data were collected at baseline and postintervention using validated questionnaires, including the Patient Health Questionnaire and World Health Organization Quality of Life (QOL-BREF), among others. The intervention will last for 8 months, with monthly self-help group meetings providing support and resources.

Results: The study aims to provide evidence on the effectiveness of integrated mental health and self-care interventions for NTD patients by evaluating outcomes such as mental health status, quality of life (QOL), and socioeconomic factors.

Conclusion: This trial aims to inform policy and practice by demonstrating the potential benefits of integrating mental health services within the care framework for individuals affected by NTDs in Nigeria. If successful, the findings will contribute to the enhancement of healthcare delivery and may be incorporated into the National Tuberculosis and Leprosy Control Program for broader implementation across the country.Trial registration: PACTR Registration number: PACTR202404852537141.https://pactr.samrc.ac.za/Default.aspx?Logout=TrueRetrospectively registered.

重新评估分枝杆菌在被忽视的热带病中的意义:尼日利亚的一项研究方案。
背景:被忽视的热带疾病(NTDs)严重影响着患者的身心健康,尤其是在尼日利亚。本研究旨在评估将心理健康服务与麻风病、布路里溃疡(BU)和淋巴丝虫病(LF)患者的自我护理实践相结合的效果。研究还将探讨经过培训的医护人员(HCWs)和NTD倡导者(NTD-Cs)在提高麻风病人健康水平方面的作用:方法:在麻风病、BU 或 LF 发病率最高的四个地方政府区域(集群)开展集群随机对照试验。试验有目的性地选取集群,并将其随机分为干预组和对照组:三个集群接受干预,一个集群作为对照。干预措施包括 (a) 由 NTD-Cs 提供心理健康和自我保健干预。(b) 由医护人员进行心理健康和自我护理干预。(c) 仅由医护人员进行自我护理干预。 d) 对照组接受标准护理。在基线和干预后使用有效问卷收集数据,包括病人健康问卷和世界卫生组织生活质量问卷(QOL-BREF)等。干预将持续 8 个月,每月举行一次自助小组会议,提供支持和资源:该研究旨在通过评估心理健康状况、生活质量(QOL)和社会经济因素等结果,为针对 NTD 患者的综合心理健康和自我护理干预措施的有效性提供证据:本试验旨在通过证明将心理健康服务纳入尼日利亚 NTD 患者护理框架的潜在益处,为政策和实践提供参考。如果试验成功,研究结果将有助于加强医疗保健服务,并可纳入国家结核病和麻风病控制计划,在全国范围内更广泛地实施:试验注册:PACTR 注册号PACTR202404852537141.https://pactr.samrc.ac.za/Default.aspx?Logout=TrueRetrospectively 注册。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.20
自引率
25.00%
发文量
62
审稿时长
7 weeks
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