Expediting pathogen genomics adoption for enhanced foodborne disease surveillance in Africa.

IF 9.7 1区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
EBioMedicine Pub Date : 2025-01-01 Epub Date: 2024-12-18 DOI:10.1016/j.ebiom.2024.105500
Aquillah M Kanzi, Stella I Smith, Chisomo Msefula, John Mwaba, Abraham Ajayi, Geoffrey Kwenda, Collins K Tanui, Anthony M Smith, Linda A Bester, Firehiwot A Derra, Kaunda Yamba, Daniel L Banda, John B Kalule, Happiness H Kumburu, Yasmina J Fakim, Nyasha Sithole, Patrick M K Njage, Francis F Chikuse, Pascale Ondoa, Sofonias K Tessema, Ebenezer Foster-Nyarko
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引用次数: 0

Abstract

The role of genomics in public health surveillance has been accentuated by its crucial contributions during the COVID-19 pandemic, demonstrating its potential in addressing global disease outbreaks. While Africa has made strides in expanding multi-pathogen genomic surveillance, the integration into foodborne disease (FBD) surveillance remains nascent. Here we highlight the critical components to strengthen and scale-up the integration of whole genome sequencing (WGS) in foodborne disease surveillance across the continent. We discuss priority use-cases for FBD, and strategies for the implementation. We also highlight the major challenges such as data management, policy and regulatory frameworks, stakeholder engagement, the need for multidisciplinary collaborations and the importance of robust monitoring and evaluation, aiming to bolster Africa's preparedness and response to future health threats.

加快采用病原体基因组学来加强非洲食源性疾病监测。
基因组学在2019冠状病毒病大流行期间的重要贡献,突显了其在公共卫生监测中的作用,显示了其在应对全球疾病暴发方面的潜力。虽然非洲在扩大多病原体基因组监测方面取得了长足进展,但将其纳入食源性疾病监测仍处于初级阶段。在此,我们强调了加强和扩大全基因组测序(WGS)在整个非洲大陆食源性疾病监测中的整合的关键组成部分。我们讨论了FBD的优先级用例和实现策略。我们还强调主要挑战,如数据管理、政策和监管框架、利益攸关方参与、多学科合作的必要性以及旨在加强非洲对未来健康威胁的准备和应对的强有力监测和评估的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
EBioMedicine
EBioMedicine Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
17.70
自引率
0.90%
发文量
579
审稿时长
5 weeks
期刊介绍: eBioMedicine is a comprehensive biomedical research journal that covers a wide range of studies that are relevant to human health. Our focus is on original research that explores the fundamental factors influencing human health and disease, including the discovery of new therapeutic targets and treatments, the identification of biomarkers and diagnostic tools, and the investigation and modification of disease pathways and mechanisms. We welcome studies from any biomedical discipline that contribute to our understanding of disease and aim to improve human health.
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