Organic photoelectrochemical transistor based on titanium dioxide nanorods for detection of Microcystin-LR.

IF 5.6 1区化学 Q1 CHEMISTRY, ANALYTICAL

Talanta Pub Date : 2024-12-16 DOI:10.1016/j.talanta.2024.127401

Jiahe Chen, Jiaxin Lv, Yue Liu, Jia-Hao Chen, Xue Wang, Hong Zhou

引用次数: 0

Abstract

A more efficient signal amplification strategy is needed to improve the performance of promising photoelectrochemical sensors (PEC). Organic photoelectrochemical transistor (OPECT) sensors are of growing interest in many fields, but their potential has not yet been widely exploited and remains a challenge. In this study, a novel organic photoelectrochemical transistor aptamer (OPECT) biosensor combining photoelectrochemical analysis and organic electrochemical transistor with AgI-TiO₂ (AgI-TNs) as photoreactive material and target-specific DNA chain reaction hybridization as signal amplifier for microcystin-LR detection was developed. The developed sensor performs highly sensitive detection with a linear range of 0.1 fg mL^-1-10 pg mL^-1 and a low detection limit of 0.079 fg mL^-1. The development of the biosensitive OPECT platform is a promising tool for MC-LR detection, meanwhile it can also be used to detect other contaminants in freshwater environments.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Talanta 化学-分析化学

CiteScore

12.30

自引率

4.90%

发文量

861

审稿时长

29 days

期刊介绍： Talanta provides a forum for the publication of original research papers, short communications, and critical reviews in all branches of pure and applied analytical chemistry. Papers are evaluated based on established guidelines, including the fundamental nature of the study, scientific novelty, substantial improvement or advantage over existing technology or methods, and demonstrated analytical applicability. Original research papers on fundamental studies, and on novel sensor and instrumentation developments, are encouraged. Novel or improved applications in areas such as clinical and biological chemistry, environmental analysis, geochemistry, materials science and engineering, and analytical platforms for omics development are welcome. Analytical performance of methods should be determined, including interference and matrix effects, and methods should be validated by comparison with a standard method, or analysis of a certified reference material. Simple spiking recoveries may not be sufficient. The developed method should especially comprise information on selectivity, sensitivity, detection limits, accuracy, and reliability. However, applying official validation or robustness studies to a routine method or technique does not necessarily constitute novelty. Proper statistical treatment of the data should be provided. Relevant literature should be cited, including related publications by the authors, and authors should discuss how their proposed methodology compares with previously reported methods.