{"title":"Cover Feature: Zn(II)-Curcumin Complexes-Based Anticancer Agents (ChemMedChem 23/2024)","authors":"Rajdeep Mondal, Muthukumar Keerthana, Nanjan Pandurangan, Sankarasekaran Shanmugaraju","doi":"10.1002/cmdc.202482302","DOIUrl":null,"url":null,"abstract":"<p>This cover image highlights the structure and anticancer properties of Zn(II)-curcumin complexes. Curcumin whose structure is given in yellow reacts with Zn(II) ion to form the fluorescent green colored Zn(II)-curcumin complex. The two DNA double helix structures represent the DNA binding potential of Zn(II)-curcumin complexes. The cell membrane in cyan and cell organelle in blue indicate the cellular uptake and internalization of Zn(II)-curcumin complex. The white bulb highlights the light irradiation of curcumin derivatives. More details can be found in the article 10.1002/cmdc.202400558 by Sankarasekaran Shanmugaraju and co-workers.<figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":147,"journal":{"name":"ChemMedChem","volume":"19 23","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cmdc.202482302","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemMedChem","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cmdc.202482302","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
This cover image highlights the structure and anticancer properties of Zn(II)-curcumin complexes. Curcumin whose structure is given in yellow reacts with Zn(II) ion to form the fluorescent green colored Zn(II)-curcumin complex. The two DNA double helix structures represent the DNA binding potential of Zn(II)-curcumin complexes. The cell membrane in cyan and cell organelle in blue indicate the cellular uptake and internalization of Zn(II)-curcumin complex. The white bulb highlights the light irradiation of curcumin derivatives. More details can be found in the article 10.1002/cmdc.202400558 by Sankarasekaran Shanmugaraju and co-workers.
期刊介绍：
Quality research. Outstanding publications. With an impact factor of 3.124 (2019), ChemMedChem is a top journal for research at the interface of chemistry, biology and medicine. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
ChemMedChem publishes primary as well as critical secondary and tertiary information from authors across and for the world. Its mission is to integrate the wide and flourishing field of medicinal and pharmaceutical sciences, ranging from drug design and discovery to drug development and delivery, from molecular modeling to combinatorial chemistry, from target validation to lead generation and ADMET studies. ChemMedChem typically covers topics on small molecules, therapeutic macromolecules, peptides, peptidomimetics, and aptamers, protein-drug conjugates, nucleic acid therapies, and beginning 2017, nanomedicine, particularly 1) targeted nanodelivery, 2) theranostic nanoparticles, and 3) nanodrugs.
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