A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.

IF 1.2 4区 医学 Q3 NURSING
Megan Miller, Molly Meyers, Annona Martin, Stephanie Napolitano, Caroline Dorsen, Andrew Penn, William E Rosa
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引用次数: 0

Abstract

Psychedelic-assisted therapy (PAT) involves supported experiences with psychedelic medicines in carefully curated environments. Early evidence suggests possible utility of PAT for addressing psychosocial-spiritual-existential concerns, yet gaps remain in understanding findings related to PAT's role in palliative care. This rapid review aims to synthesize current literature on applications of PAT in the context of palliative care. Through a systematic process, we identified 34 articles published between January 2021 and July 2024. Protocols varied yet included common components of participant screening, preparation, dosing, and integration. Psilocybin was the most commonly studied compound. Results support safety and initial efficacy of PAT for psycho-spiritual-existential outcomes among carefully screened and highly homogonous samples of patients with serious illness (predominantly cancer). Current efforts and challenges around integrating PAT into systems of palliative care were highlighted. Additional work is needed to (1) explore PAT's safety and efficacy within more diverse samples and contexts, (2) train palliative care providers on PAT, (3) determine systems of care delivery best suited for translation of PAT into practice, and (4) begin developing policy solutions to support safe and equitable access to PAT. Because many patients lack access to basic psychosocial-spiritual-existential care, careful consideration is needed around integration of PAT. The psychedelic substances which are the topic of this article are not currently FDA approved for use in the United States.

姑息治疗背景下致幻剂辅助治疗的快速回顾。
迷幻辅助治疗(PAT)包括在精心策划的环境中使用迷幻药物的支持体验。早期证据表明,PAT可能用于解决心理-社会-精神-存在问题,但在理解与PAT在姑息治疗中的作用有关的发现方面仍存在差距。这篇快速的综述旨在综合目前关于PAT在姑息治疗中的应用的文献。通过系统的过程,我们确定了2021年1月至2024年7月期间发表的34篇文章。方案各不相同,但包括参与者筛选、准备、给药和整合的共同组成部分。裸盖菇素是最常被研究的化合物。结果支持在精心筛选和高度同质的严重疾病(主要是癌症)患者样本中,PAT对心理-精神-存在结局的安全性和初步有效性。强调了将PAT纳入姑息治疗系统的当前努力和挑战。需要做更多的工作来(1)在更多样化的样本和背景下探索PAT的安全性和有效性,(2)培训姑息治疗提供者,(3)确定最适合将PAT转化为实践的护理提供系统,以及(4)开始制定政策解决方案,以支持安全和公平地获得PAT。由于许多患者缺乏基本的心理-社会-精神-存在关怀,因此需要仔细考虑PAT的整合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.60
自引率
11.10%
发文量
203
审稿时长
6-12 weeks
期刊介绍: Journal of Hospice & Palliative Nursing (JHPN) is the official journal of the Hospice & Palliative Nurses Association and is the professional, peer-reviewed journal for nurses in hospice and palliative care settings. Focusing on the clinical, educational and research aspects of care, JHPN offers current and reliable information on end of life nursing. Feature articles in areas such as symptom management, ethics, and futility of care address holistic care across the continuum. Book and article reviews, clinical updates and case studies create a journal that meets the didactic and practical needs of the nurse caring for patients with serious illnesses in advanced stages.
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