{"title":"Profile of co-occurring or secondary infections among COVID-19 patients with HBOT: a single-center retrospective study.","authors":"Peixia Yu, Hairu Wang, Ziyang Li, Junyan Zhang, Shuang Wei, Zhifeng Xue, Bozheng Zhang, Qi Mei, Zhengtao Wang, Yani Zhao, Qing Niu, Pingzhi Wang","doi":"10.3855/jidc.20460","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This study was designed to describe the profile of co-occurring or secondary infections in hospitalized coronavirus disease 2019 (COVID-19) patients undergoing hyperbaric oxygen therapy (HBOT) and those without.</p><p><strong>Methodology: </strong>Out of 716 COVID-19 patients, 79 cases of co-occurring or secondary infections were included. These patients were categorized into two groups based on their usage of HBOT. The basic information and laboratory examinations, especially pathogen-related results were collected from the medical records. The rate of co-occurring or secondary infections, distribution of pathogens, infection sites, and results of antimicrobial susceptibility testing were analyzed.</p><p><strong>Results: </strong>Among the 79 COVID-19 patients examined, there were 73 cases of infections, including 58 co-occurring infections, 14 secondary infections, and 1 mixed infection in the non-HBOT group. There were 6 cases with co-occurring or secondary infections in the HBOT group. Influenza virus was predominant in the co-occurring or secondary infections of COVID-19 patients, but it was not detected in patients undergoing HBOT. Klebsiella pneumoniae, Corynebacterium striatum, and Acinetobacter baumannii were the main strains isolated among patients with HBOT. The multidrug-resistant organisms (MDROs) strains of Escherichia coli, Klebsiella aerogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecium were detected from COVID-19 patients treated with HBOT.</p><p><strong>Conclusions: </strong>This study described the profile of in-hospital co-occurring or secondary infections in COVID-19 patients from North China. Management of the co-occurring or secondary infections, especially MDROs infections treated with HBOT, including but not limited to COVID-19, should be strengthened.</p>","PeriodicalId":49160,"journal":{"name":"Journal of Infection in Developing Countries","volume":"18 11","pages":"1663-1670"},"PeriodicalIF":1.4000,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infection in Developing Countries","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3855/jidc.20460","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: This study was designed to describe the profile of co-occurring or secondary infections in hospitalized coronavirus disease 2019 (COVID-19) patients undergoing hyperbaric oxygen therapy (HBOT) and those without.
Methodology: Out of 716 COVID-19 patients, 79 cases of co-occurring or secondary infections were included. These patients were categorized into two groups based on their usage of HBOT. The basic information and laboratory examinations, especially pathogen-related results were collected from the medical records. The rate of co-occurring or secondary infections, distribution of pathogens, infection sites, and results of antimicrobial susceptibility testing were analyzed.
Results: Among the 79 COVID-19 patients examined, there were 73 cases of infections, including 58 co-occurring infections, 14 secondary infections, and 1 mixed infection in the non-HBOT group. There were 6 cases with co-occurring or secondary infections in the HBOT group. Influenza virus was predominant in the co-occurring or secondary infections of COVID-19 patients, but it was not detected in patients undergoing HBOT. Klebsiella pneumoniae, Corynebacterium striatum, and Acinetobacter baumannii were the main strains isolated among patients with HBOT. The multidrug-resistant organisms (MDROs) strains of Escherichia coli, Klebsiella aerogenes, Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecium were detected from COVID-19 patients treated with HBOT.
Conclusions: This study described the profile of in-hospital co-occurring or secondary infections in COVID-19 patients from North China. Management of the co-occurring or secondary infections, especially MDROs infections treated with HBOT, including but not limited to COVID-19, should be strengthened.
期刊介绍：
The Journal of Infection in Developing Countries (JIDC) is an international journal, intended for the publication of scientific articles from Developing Countries by scientists from Developing Countries.
JIDC is an independent, on-line publication with an international editorial board. JIDC is open access with no cost to view or download articles and reasonable cost for publication of research artcles, making JIDC easily availiable to scientists from resource restricted regions.
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