Biased allele transmission for herbicide resistance: a conditional gene drive.

IF 3.6 3区 生物学 Q1 PLANT SCIENCES
Planta Pub Date : 2024-12-18 DOI:10.1007/s00425-024-04595-9
Anthony J Conner, Jeanne M E Jacobs
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引用次数: 0

Abstract

Main conclusion: Herbicide application to plants heterozygous for herbicide resistance results in distorted segregation favoring resistant allele transmission resulting in a conditional gene drive. Brassica napus plants heterozygous for an allele conferring sulfonylurea resistance at a single locus exhibit normal Mendelian inheritance. However, following application of the herbicide, highly distorted segregation of herbicide resistance occurs among progeny. Screening progeny from controlled crosses demonstrated that the herbicide imposes in planta gametic selection against pollen and ovules with the recessive allele for herbicide susceptibility, as well as embryonic selection against embryos homozygous for the susceptible allele. Such inducible biased inheritance represents a conditional form of allele transmission following herbicide application and mimics a natural gene drive. We postulate that natural gene drives are common in plant populations and can operate in a conditional manner resulting in non-Mendelian inheritance in response to abiotic and biotic stresses.

除草剂抗性的偏置等位基因传递:条件基因驱动。
主要结论:除草剂应用于具有抗除草剂杂合子的植物中,会导致偏向抗性等位基因传播的扭曲分离,从而形成条件基因驱动。甘蓝型油菜单位点抗磺酰脲等位基因杂合表现为正常的孟德尔遗传。然而,在施用除草剂后,后代之间出现了高度扭曲的除草剂抗性分离。对对照杂交后代的筛选表明,除草剂对具有除草剂敏感性的隐性等位基因的花粉和胚珠施加配子选择,对具有除草剂敏感性等位基因的纯合子胚胎施加胚胎选择。这种可诱导的偏遗传代表了除草剂施用后等位基因传播的条件形式,并模仿了自然基因驱动。我们假设自然基因驱动在植物种群中是常见的,并且可以以有条件的方式操作,导致非孟德尔遗传,以响应非生物和生物胁迫。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Planta
Planta 生物-植物科学
CiteScore
7.20
自引率
2.30%
发文量
217
审稿时长
2.3 months
期刊介绍: Planta publishes timely and substantial articles on all aspects of plant biology. We welcome original research papers on any plant species. Areas of interest include biochemistry, bioenergy, biotechnology, cell biology, development, ecological and environmental physiology, growth, metabolism, morphogenesis, molecular biology, new methods, physiology, plant-microbe interactions, structural biology, and systems biology.
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