Effects of the first frozen-thawed embryo transfer time on pregnancy outcomes after progestin primed ovarian stimulation regimen.

Abstract

This was an original article, mainly explored the effects of the first frozen-thawed embryo transfer (FET) time on pregnancy outcomes after progestin primed ovarian stimulation (PPOS) regimen. Our study implemented a retrospective analysis of 315 infertile patients who underwent in vitro fertilization and embryo transfer (IVF-ET) treatment from January 2021 to June 2023. Patients were divided into three groups based on their first FET time. Group A prepared FET at the first menstrual period after oocyte retrieval; Group B prepared FET at the second menstrual period,; while Group C prepared FET at the third menstrual period. The general information of patients, clinical data of PPOS cycle, clinical data of FET cycle, along with pregnancy outcomes were compared in three groups. The results showed no significant differences in general information of patients, clinical data of PPOS cycle, clinical data of FET cycle and pregnancy outcomes among three groups (P>0.05). The results showed that the choice of the first FET time for whole embryo freezing patients had no significant effect on the outcome of assisted pregnancy. We conclude that the first menstrual cycle after the oocyte retrieval cycle can be considered to select the appropriate FET scheme and performance of the FET.