Case management strategy enhances virological response in people living with human immunodeficiency virus in a resource-limited region in Southwest China: a real-world prospective observational study.
Xiaozhen Song, Juan Zheng, Liyu Chen, Fanghua Ma, Changmin Li, Junjie Wang, Lingyao Du, Hong Tang
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引用次数: 0
Abstract
This study assessed the effectiveness of case management compared to that of standard care in improving treatment outcomes for first-time antiretroviral therapy (ART) patients in Liangshan Prefecture, China. First-time ART patients (total n = 828) were divided into the Standard Care Group (SCG, n = 419) and Case Management Group (CMG, n = 409). At week 48, the CMG showed higher retention rates (97.7% vs. 93.6%), better adherence, and more complete virological responses (84.2% vs. 64.0%) compared to the SCG. These findings suggest that case management improves adherence and virological suppression in resource-limited areas, though further research is needed to confirm its broader applicability.
本研究评估了病例管理与标准护理在改善中国凉山州首次抗逆转录病毒治疗(ART)患者治疗结果方面的有效性。首次ART患者共828例,分为标准治疗组(SCG, n = 419)和病例管理组(CMG, n = 409)。在第48周,与SCG相比,CMG显示出更高的保留率(97.7%对93.6%),更好的依从性和更完整的病毒学应答(84.2%对64.0%)。这些发现表明,病例管理改善了资源有限地区的依从性和病毒学抑制,尽管需要进一步的研究来证实其更广泛的适用性。
期刊介绍:
AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered