Issue highlights

IF 2.4 4区 医学 Q1 PEDIATRICS
Acta Paediatrica Pub Date : 2024-12-09 DOI:10.1111/apa.17520
Anna Käll, Hugo Lagercrantz
{"title":"Issue highlights","authors":"Anna Käll,&nbsp;Hugo Lagercrantz","doi":"10.1111/apa.17520","DOIUrl":null,"url":null,"abstract":"<p>Dahlén and Kimland analysed nearly 4.6 million prescriptions dispensed to more than 2 million children aged 0–17 years in Sweden.<span><sup>1</sup></span> Just under half of the children (47%) received at least one drug in 2019 and 34% received three or more different drugs. The most common drugs were for respiratory tract issues, followed by psychoanaleptics and melatonin for the nervous system and dermatologicals. The average number of prescriptions almost doubled from 2.3 in 2007 to 4.5 in 2019. Garnemark and Kindblom comment on the findings in an editorial.<span><sup>2</sup></span> https://doi.org/10.1111/apa.17425.</p><p>Height velocity is a key tool for monitoring growth and detecting serious health conditions early. Scherdel et al. have produced new annual and biannual height velocity charts for French children up to 15 years of age, using values routinely collected in primary care settings.<span><sup>3</sup></span> The median curves were close to the 1979 French and 2009 World Health Organization values, but there were important differences in the standard deviation curves. An editorial by Van Dommelen states that the same data collection method could be used by other countries to produce velocity charts with minimal extra effort.<span><sup>4</sup></span> https://doi.org/10.1111/apa.17454.</p><p>Cholestasis is highly prevalent in very low birth weight infants. It is predominantly caused by parenteral nutrition, and Oh et al. found that this condition developed at about 1 month of age.<span><sup>5</sup></span> They report that it took approximately 2 months for direct bilirubin to normalise, even when parenteral nutrition ceased and full enteral feeding was established. More time was required to normalise aspartate transferase and alanine aminotransferase levels. An editorial by Teng et al. states that understanding the dynamics of biochemical liver markers in pre-term infants with parenteral nutrition-associated cholestasis may prevent unnecessary invasive examinations.<span><sup>6</sup></span> https://doi.org/10.1111/apa.17427.</p><p>Tracheomalacia causes considerable morbidity in children and the best treatment options are still being debated. Møller et al. present a case series of seven Danish children who underwent surgical interventions, including tracheopexy and aortopexy, to reduce the respiratory symptoms caused by tracheal collapse. They report favourable clinical outcomes, particularly when there was an early intervention, and discuss the indications, timing and potential benefits of this surgery.<span><sup>7</sup></span> https://doi.org/10.1111/apa.17452.</p><p>Neonatal intensive care has improved for infants born extremely preterm, but it has not been matched by similar progress in post-discharge interventions. Baraldi et al. conducted a randomised clinical trial of 130 children born extremely preterm, to evaluate an interaction-based home-visiting programme during the first year after discharge.<span><sup>8</sup></span> The controls received standard care. No difference in overall parent–child emotional availability was found between the two groups. However, when their mothers were depressed, children in the intervention group showed superior involvement behaviour to the controls. In another paper, Lapage et al. report that parenting stress in infancy was associated with poorer neurodevelopment in 24-month-old children with congenital heart disease.<span><sup>9</sup></span> https://doi.org/10.1111/apa.17399.</p><p><b>Figures:</b> istockphoto</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":"114 1","pages":"6-7"},"PeriodicalIF":2.4000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/apa.17520","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Paediatrica","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/apa.17520","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

Abstract

Dahlén and Kimland analysed nearly 4.6 million prescriptions dispensed to more than 2 million children aged 0–17 years in Sweden.1 Just under half of the children (47%) received at least one drug in 2019 and 34% received three or more different drugs. The most common drugs were for respiratory tract issues, followed by psychoanaleptics and melatonin for the nervous system and dermatologicals. The average number of prescriptions almost doubled from 2.3 in 2007 to 4.5 in 2019. Garnemark and Kindblom comment on the findings in an editorial.2 https://doi.org/10.1111/apa.17425.

Height velocity is a key tool for monitoring growth and detecting serious health conditions early. Scherdel et al. have produced new annual and biannual height velocity charts for French children up to 15 years of age, using values routinely collected in primary care settings.3 The median curves were close to the 1979 French and 2009 World Health Organization values, but there were important differences in the standard deviation curves. An editorial by Van Dommelen states that the same data collection method could be used by other countries to produce velocity charts with minimal extra effort.4 https://doi.org/10.1111/apa.17454.

Cholestasis is highly prevalent in very low birth weight infants. It is predominantly caused by parenteral nutrition, and Oh et al. found that this condition developed at about 1 month of age.5 They report that it took approximately 2 months for direct bilirubin to normalise, even when parenteral nutrition ceased and full enteral feeding was established. More time was required to normalise aspartate transferase and alanine aminotransferase levels. An editorial by Teng et al. states that understanding the dynamics of biochemical liver markers in pre-term infants with parenteral nutrition-associated cholestasis may prevent unnecessary invasive examinations.6 https://doi.org/10.1111/apa.17427.

Tracheomalacia causes considerable morbidity in children and the best treatment options are still being debated. Møller et al. present a case series of seven Danish children who underwent surgical interventions, including tracheopexy and aortopexy, to reduce the respiratory symptoms caused by tracheal collapse. They report favourable clinical outcomes, particularly when there was an early intervention, and discuss the indications, timing and potential benefits of this surgery.7 https://doi.org/10.1111/apa.17452.

Neonatal intensive care has improved for infants born extremely preterm, but it has not been matched by similar progress in post-discharge interventions. Baraldi et al. conducted a randomised clinical trial of 130 children born extremely preterm, to evaluate an interaction-based home-visiting programme during the first year after discharge.8 The controls received standard care. No difference in overall parent–child emotional availability was found between the two groups. However, when their mothers were depressed, children in the intervention group showed superior involvement behaviour to the controls. In another paper, Lapage et al. report that parenting stress in infancy was associated with poorer neurodevelopment in 24-month-old children with congenital heart disease.9 https://doi.org/10.1111/apa.17399.

Figures: istockphoto

Abstract Image

问题突出
dahlsamn和Kimland分析了瑞典200多万名0-17岁儿童的近460万张处方。2019年,近一半(47%)的儿童至少服用了一种药物,34%的儿童服用了三种或三种以上不同的药物。最常见的药物是用于呼吸道疾病,其次是用于神经系统和皮肤病的精神镇痛药和褪黑素。平均处方数量几乎翻了一番,从2007年的2.3张增加到2019年的4.5张。加内马克和金布洛姆在一篇社论中评论了这一发现。2 https://doi.org/10.1111/apa.17425.Height速度是监测生长和早期发现严重健康状况的关键工具。Scherdel等人制作了法国15岁以下儿童的新的年度和两年一次的身高速度图表,使用的是在初级保健机构中常规收集的数值中位数曲线接近1979年法国和2009年世界卫生组织的值,但标准差曲线存在重要差异。Van Dommelen的一篇社论指出,其他国家可以使用同样的数据收集方法,以最少的额外努力制作速度图。4 https://doi.org/10.1111/apa.17454.Cholestasis在非常低出生体重的婴儿中非常普遍。它主要是由肠外营养引起的,Oh等人发现这种情况发生在大约1个月大的时候他们报告说,直接胆红素恢复正常需要大约2个月的时间,即使在停止肠外营养和建立完全肠内喂养的情况下也是如此。使天冬氨酸转移酶和丙氨酸转氨酶水平正常化需要更多的时间。Teng等人的一篇社论指出,了解肠外营养相关性胆汁淤积症早产儿肝脏生化标志物的动态可以防止不必要的侵入性检查。6 https://doi.org/10.1111/apa.17427.Tracheomalacia在儿童中引起相当大的发病率,最佳治疗方案仍在讨论中。Møller等人报道了7名丹麦儿童的病例系列,他们接受了包括气管切开和主动脉切开在内的手术干预,以减轻气管塌陷引起的呼吸道症状。他们报告了良好的临床结果,特别是在早期干预的情况下,并讨论了手术的适应症、时机和潜在益处。7 https://doi.org/10.1111/apa.17452.Neonatal极度早产婴儿的重症监护得到了改善,但在出院后干预方面并没有取得类似的进展。Baraldi等人对130名极度早产儿童进行了随机临床试验,以评估出院后第一年以互动为基础的家访计划对照组接受标准护理。两组之间的整体亲子情感可得性没有差异。然而,当他们的母亲抑郁时,干预组的孩子表现出比对照组更好的参与行为。在另一篇论文中,Lapage等人报告说,婴儿时期的父母压力与24个月大的先天性心脏病患儿较差的神经发育有关。9 https://doi.org/10.1111/apa.17399.Figures: istockphoto
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Acta Paediatrica
Acta Paediatrica 医学-小儿科
CiteScore
6.50
自引率
5.30%
发文量
384
审稿时长
2-4 weeks
期刊介绍: Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信