Enzymatic azide synthesis by ATP-dependent synthetase

IF 11.5 Q1 CHEMISTRY, PHYSICAL

Chem Catalysis Pub Date : 2024-12-19 DOI:10.1016/j.checat.2024.101226

Yohei Katsuyama

引用次数: 0

Abstract

In a recent issue of Nature Chemistry, Zhang and coworkers showed that the ATP-dependent N-nitrosylase Tri17 can catalyze azide synthesis. Tri17 is a promiscuous enzyme that can catalyze N-nitrosylation of various substrates. When specific substrates were used, it also catalyzed the dehydration of the N-nitroso moiety to synthesize an azide moiety.

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在最近一期的《自然-化学》（Nature Chemistry）杂志上，Zhang 及其同事发现，依赖 ATP 的 N-亚硝基酶 Tri17 可以催化叠氮化物的合成。Tri17 是一种杂化酶，可以催化各种底物的 N-亚硝基化。当使用特定底物时，它还能催化 N-亚硝基脱水合成叠氮化物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chem Catalysis

CiteScore

10.50

自引率

6.40%

发文量

期刊介绍： Chem Catalysis is a monthly journal that publishes innovative research on fundamental and applied catalysis, providing a platform for researchers across chemistry, chemical engineering, and related fields. It serves as a premier resource for scientists and engineers in academia and industry, covering heterogeneous, homogeneous, and biocatalysis. Emphasizing transformative methods and technologies, the journal aims to advance understanding, introduce novel catalysts, and connect fundamental insights to real-world applications for societal benefit.