Cu-MOF-based targeted nanomedicine utilizing biorthogonally catalyzed chemotherapy and chemodynamic therapy with spatiotemporal orchestration to treat hepatocellular carcinoma†

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2024-12-03 DOI:10.1039/d4cc05890a

Xiuyan Wan , Yu Zhang , Huiwen Zhang , Wei Pan , Xincheng Qiao , Na Li , Bo Tang

引用次数: 0

Abstract

A nanomedicine was developed using a Cu-based metal–organic framework (MOF) to co-deliver Cu(i) and prodrugs for targeted biorthogonally catalyzed chemotherapy and chemodynamic therapy of hepatocellular carcinoma.

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基于 Cu-MOF 的靶向纳米药物，利用生物催化化疗和时空协调的化学动力疗法治疗肝细胞癌

利用Cu基金属有机框架（MOF）开发了一种纳米药物，可将Cu(I)和前药共同递送，用于靶向生物正交催化肝癌化疗和化疗动力学治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.