Effect of the consumption of cashew nut (Anacardium occidentale l.) flour-based biscuits in overweight children: a pilot randomized clinical trial.

IF 2.5 4区 医学 Q3 BUSINESS
Letícia Bezerra Brito, Brenna Oliveira Leal, Janaína Ribeiro da Silva, Kelly Maria Pereira Barbosa, Vinícius Teixeira da Silva, Andressa Silva Costa, Yroan Paula Landim, Lívia Maia Pascoal, Marcelino Santos Neto, Ana Lúcia Fernandes Pereira, Virgínia Kelly Gonçalves Abreu, Virlane Kelly Lima Hunaldo, José de Ribamar Macedo Costa, Ana Cristina Pereira de Jesus Costa, Márcio Flávio Moura de Araújo
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引用次数: 0

Abstract

Background: cashew nut is an almond known for its cardiovascular benefits in adults and weight gain effects in malnourished children, as supported by research. However, its impact on overweight children remains unexplored.

Objective: to analyze the effect of consuming biscuits made with cashew nut flour on the blood glucose and serum triglyceride levels of children with overweight/obesity over four weeks.

Methods: a pilot, randomized, open-label clinical study was conducted with 19 overweight children (11 in intervention group 1 [G1] and 8 in group 2 [G2], aged between 7 and 15 years. Over four consecutive weeks, they consumed, daily, three biscuits with 50 % cashew nut flour composition (G1) and six biscuits with 50 % cashew nut flour composition (G2). The biomarkers analyzed were glycated hemoglobin (HbA1c), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and total cholesterol (TC) at baseline and seven days post-biscuit consumption.

Results: post-experiment, the TG (p = 0.153), HDL-C (p = 0.895), and TC (p = 0.122) biomarkers showed no significant changes. LDL-C levels experienced a slight but statistically significant increase of 0.52 % across all participants (p = 0.031). In contrast, non-HDL cholesterol levels saw a minor yet significant reduction of -1.7 % in serum concentration (p = 0.014). Independent of group allocation, the participants' HbA1c and average blood glucose levels significantly decreased by 12.1 % (p < 0.001) and 17.9 % (p < 0.001), respectively (Cohen's Δ = 1, in both instances).

Conclusion: consumption of biscuits containing cashew nut flour by overweight/obese children positively affected the reduction of blood glucose and non-HDL cholesterol biomarkers in both groups, regardless of the formulations used.

背景:腰果是一种杏仁,因其对成人心血管的益处和对营养不良儿童体重增加的影响而闻名,这一点已得到研究证实。目的:分析连续四周食用腰果粉饼干对超重/肥胖儿童血糖和血清甘油三酯水平的影响。方法:对 19 名超重儿童(干预组 1 [G1] 11 名,干预组 2 [G2] 8 名,年龄在 7 至 15 岁之间)进行了一项试验性、随机、开放标签临床研究。在连续四周的时间里,他们每天食用 3 块腰果粉含量为 50% 的饼干(G1)和 6 块腰果粉含量为 50% 的饼干(G2)。分析的生物标志物包括基线和食用饼干后七天的糖化血红蛋白(HbA1c)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和总胆固醇(TC)。结果:实验后,总胆固醇(p = 0.153)、高密度脂蛋白胆固醇(p = 0.895)和总胆固醇(p = 0.122)生物标志物没有发生显著变化。所有参与者的低密度脂蛋白胆固醇(LDL-C)水平略微上升了 0.52%,但具有统计学意义(p = 0.031)。相比之下,非高密度脂蛋白胆固醇的血清浓度略有下降,但降幅明显,为-1.7%(p = 0.014)。结论:无论使用哪种配方,超重/肥胖儿童食用含腰果粉的饼干都会对降低两组儿童的血糖和非高密度脂蛋白胆固醇生物标志物产生积极影响。
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来源期刊
Nutricion hospitalaria
Nutricion hospitalaria 医学-营养学
CiteScore
1.90
自引率
8.30%
发文量
181
审稿时长
3-6 weeks
期刊介绍: The journal Nutrición Hospitalaria was born following the SENPE Bulletin (1981-1983) and the SENPE journal (1984-1985). It is the official organ of expression of the Spanish Society of Clinical Nutrition and Metabolism. Throughout its 36 years of existence has been adapting to the rhythms and demands set by the scientific community and the trends of the editorial processes, being its most recent milestone the achievement of Impact Factor (JCR) in 2009. Its content covers the fields of the sciences of nutrition, with special emphasis on nutritional support.
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