The Associations Between Life's Essential 8 and Diarrhea and Constipation: Results from the 2005-2010 NHANES.

IF 3 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Clinical and Translational Gastroenterology Pub Date : 2024-12-18 DOI:10.14309/ctg.0000000000000801

Xin Yang, Shengjie Ding, Jinlu Guo, Shuang Peng, Zhiqing Duan, Shi Liu

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引用次数: 0

Abstract

Background and aims: Few studies have investigated the association between Life's Essential 8 (LE8) and abnormal bowel health. We aimed to investigate the relationship between LE8 and diarrhea and constipation in the adult population of the United States.

Methods: This cross-sectional study, based on population data, utilized information from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2010. Diarrhea and constipation were classified based on Bristol Stool Form Scale and stool frequency. LE8 score is composed of four health behaviors (diet, physical activity, nicotine exposure, and sleep health) and four health factors (body mass index, blood lipids, blood glucose, and blood pressure) and is classified into low (0-49), moderate (50-79), and high (80-100) cardiovascular health (CVH) groups. Weighted logistic regression and restricted cubic splines were employed to analyze the relationship between the LE8 score and abnormal bowel health.

Results: The study comprised 12,369 subjects aged 20 years or older, among whom 1,279 (9.7%) had constipation and 1,097 (7.6%) had diarrhea. After adjusting for potential confounders, we observed negative associations between LE8 scores and diarrhea (OR: 0.60, 95% CI: 0.39-0.93), whereas the association between LE8 scores and constipation was not statistically significant (OR: 0.82, 95% CI: 0.59-1.13). Additionally, health behavior scores and health factor scores are associated with constipation.

Conclusions: Higher LE8 levels are associated with a lower incidence of diarrhea, but not constipation.

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来源期刊

Clinical and Translational Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

7.00

自引率

0.00%

发文量

114

审稿时长

16 weeks

期刊介绍： Clinical and Translational Gastroenterology (CTG), published on behalf of the American College of Gastroenterology (ACG), is a peer-reviewed open access online journal dedicated to innovative clinical work in the field of gastroenterology and hepatology. CTG hopes to fulfill an unmet need for clinicians and scientists by welcoming novel cohort studies, early-phase clinical trials, qualitative and quantitative epidemiologic research, hypothesis-generating research, studies of novel mechanisms and methodologies including public health interventions, and integration of approaches across organs and disciplines. CTG also welcomes hypothesis-generating small studies, methods papers, and translational research with clear applications to human physiology or disease. Colon and small bowel Endoscopy and novel diagnostics Esophagus Functional GI disorders Immunology of the GI tract Microbiology of the GI tract Inflammatory bowel disease Pancreas and biliary tract Liver Pathology Pediatrics Preventative medicine Nutrition/obesity Stomach.