Men with type 1 diabetes had a more than 7-fold odds of elevated depressive symptoms compared to men without diabetes

IF 6.1 3区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes research and clinical practice Pub Date : 2025-01-01 DOI:10.1016/j.diabres.2024.111947

Kimberly A. Driscoll , Cristy R. Geno Rasmussen , Holly O’Donnell , Paige Trojanowski , Amy C. Alman , Amena Keshawarz , Janet K. Snell-Bergeon

{"title":"Men with type 1 diabetes had a more than 7-fold odds of elevated depressive symptoms compared to men without diabetes","authors":"Kimberly A. Driscoll , Cristy R. Geno Rasmussen , Holly O’Donnell , Paige Trojanowski , Amy C. Alman , Amena Keshawarz , Janet K. Snell-Bergeon","doi":"10.1016/j.diabres.2024.111947","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To examine: 1) differences in prevalence of elevated depressive symptoms between individuals with type 1 diabetes (T1D) and without any type of diabetes overall and by sex; and 2) associations between depressive symptoms and HbA1c, self-management behaviors, and cardiovascular health.</div><div>Research Design and Methods: Adults (n = 414) with T1D (mean age = 52 ± 9 years, mean duration = 38 ± 9 years; mean HbA1c = 7.8 ± 1.1 mg/dL or 177 mmol/L; 55 % female) and without any type of diabetes (n = 488; mean age = 51 ± 9 years; 51 % female) from the fourth study visit of CACTI, an observational study, completed questionnaires about depressive symptoms and dietary intake. Only adults with T1D completed a questionnaire about diabetes self-management. Hierarchical logistic regression models were used to examine demographic and clinical characteristics associated with depressive symptoms.</div></div><div><h3>Results</h3><div>Depressive scores were higher in people with T1D overall and in both sexes. Men with T1D had >7-fold increased odds of elevated depressive symptoms compared to men without diabetes (OR 7.4, 95 % CI: 2.1–26.4), whereas there were no increased odds in women (OR 1.4, 95 % CI: 0.6–2.9, significant sex x diabetes interaction [p = 0.03]). Higher levels of depressive symptoms were associated with both lower engagement in self-management behaviors and physical activity.</div></div><div><h3>Conclusions</h3><div>Our results demonstrate that there is an urgent need to screen adults with T1D for depressive symptoms as part of routine medical care and to test interventions to minimize their impact on physical health outcomes.</div></div>","PeriodicalId":11249,"journal":{"name":"Diabetes research and clinical practice","volume":"219 ","pages":"Article 111947"},"PeriodicalIF":6.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetes research and clinical practice","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S016882272400857X","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

To examine: 1) differences in prevalence of elevated depressive symptoms between individuals with type 1 diabetes (T1D) and without any type of diabetes overall and by sex; and 2) associations between depressive symptoms and HbA1c, self-management behaviors, and cardiovascular health.

Research Design and Methods: Adults (n = 414) with T1D (mean age = 52 ± 9 years, mean duration = 38 ± 9 years; mean HbA1c = 7.8 ± 1.1 mg/dL or 177 mmol/L; 55 % female) and without any type of diabetes (n = 488; mean age = 51 ± 9 years; 51 % female) from the fourth study visit of CACTI, an observational study, completed questionnaires about depressive symptoms and dietary intake. Only adults with T1D completed a questionnaire about diabetes self-management. Hierarchical logistic regression models were used to examine demographic and clinical characteristics associated with depressive symptoms.

Results

Depressive scores were higher in people with T1D overall and in both sexes. Men with T1D had >7-fold increased odds of elevated depressive symptoms compared to men without diabetes (OR 7.4, 95 % CI: 2.1–26.4), whereas there were no increased odds in women (OR 1.4, 95 % CI: 0.6–2.9, significant sex x diabetes interaction [p = 0.03]). Higher levels of depressive symptoms were associated with both lower engagement in self-management behaviors and physical activity.

Conclusions

Our results demonstrate that there is an urgent need to screen adults with T1D for depressive symptoms as part of routine medical care and to test interventions to minimize their impact on physical health outcomes.

查看原文本刊更多论文

与没有糖尿病的男性相比，患有1型糖尿病的男性抑郁症状升高的几率超过7倍。

目的：研究：1)1型糖尿病患者和非1型糖尿病患者抑郁症状升高的患病率总体和性别差异；2)抑郁症状与糖化血红蛋白、自我管理行为和心血管健康之间的关系。研究设计和方法:成人(n = 414)1型糖尿病患者(平均年龄 = 52 ± 9年,意味着时间 = 38 ± 9年;平均HbA1c = 7.8 ± 1.1 mg/dL或177 mmol/L；55 %女性)，没有任何类型的糖尿病(n = 488；平均年龄 = 51 ± 9岁；51（ %女性）从观察性研究CACTI的第四次研究访问中完成了关于抑郁症状和饮食摄入的问卷调查。成人1型糖尿病患者完成一份糖尿病自我管理问卷。分层逻辑回归模型用于检查与抑郁症状相关的人口学和临床特征。结果：1型糖尿病患者的抑郁得分总体上更高，无论男女。与没有糖尿病的男性相比，1型糖尿病男性抑郁症状升高的几率增加了7倍（OR 7.4, 95 % CI: 2.1-26.4），而女性的几率没有增加（OR 1.4, 95 % CI: 0.6-2.9，显著的性别 与 糖尿病相互作用[p = 0.03]）。较高水平的抑郁症状与较低的自我管理行为和体力活动相关。结论：我们的研究结果表明，迫切需要筛查成人1型糖尿病患者的抑郁症状，作为常规医疗护理的一部分，并测试干预措施，以尽量减少其对1型糖尿病结局的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Diabetes research and clinical practice 医学-内分泌学与代谢

CiteScore

10.30

自引率

3.90%

发文量

862

审稿时长

32 days

期刊介绍： Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.