The Role of P-Wave Variables in Enhancing Prediction of New-Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Annals of Noninvasive Electrocardiology Pub Date : 2024-12-18 DOI:10.1111/anec.70041

Na Yang, Xiaoyan Li, Bo Wu, Longhao Dai, Shaobin Yang, Qinning Zhang, Shaobin Jia

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引用次数: 0

Abstract

Background

After acute myocardial infarction (AMI), it is common to observe new-onset atrial fibrillation (NOAF), which is often related to a negative prognosis. Some P-wave variables (P-wave duration [PWD], P-wave amplitude, and interatrial block [IAB]), reflecting the process of electrical and structural remodeling, could predict the risk of atrial fibrillation (AF). This study aimed to assess the predictive value of P-wave variables for post-AMI NOAF.

Methods

We retrospectively analyzed 1581 AMI patients with no prior AF, using follow-up data from January 2023 to January 2024. P-wave variables were measured, and patients were grouped based on in-hospital NOAF occurrence.

Results

Overall, 164 (10.3%) of the 1581 patients had NOAF. The age (61.08 ± 12.02 vs. 67.91 ± 11.60, p < 0.001), left atrial size (36.31 ± 3.94 vs. 39.12 ± 5.51, p < 0.001), Brain Natriuretic Peptide (1588.45 ± 3346.18 vs. 3864.39 ± 6251.92, p < 0.001), P-wave variables (PWD: 102.78 ± 12.56 vs. 117.88 ± 18.81, p < 0.001; P-wave amplitude: 0.12 ± 0.04 vs. 0.13 ± 0.04, p = 0.041; interatrial block: 89.6% vs. 10.3%, p < 0.001), congestive heart failure (4.7% vs. 23.2%, p < 0.001), and Killip > 1 (25.3% vs. 55.5%, p < 0.001) showed significant differences between the non-AF and NOAF groups. P-wave variables were significantly associated with an increased risk of NOAF in multivariable regression analysis.

Conclusions

The addition of P-wave variables to AF risk factors from literature and guidelines significantly improved NOAF risk discrimination. P-wave variables were strongly associated with NOAF after AMI. Adding these variables enhanced the predictive performance for post-AMI NOAF.

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查看原文本刊更多论文

P 波变量在增强急性心肌梗死患者新发心房颤动预测中的作用》（The Role of Pave Variables in Enhanced Predicting of New-Onset Atrial Fibrillation in Patients with Acute Myocardial Infarction）。

背景：急性心肌梗死（AMI）后，常观察到新发心房颤动（NOAF），这往往与不良预后有关。一些反映电重构和结构重构过程的p波变量（p波持续时间[PWD]、p波振幅和房间传导阻滞[IAB]）可以预测心房颤动（AF）的发生风险。本研究旨在评估p波变量对ami后NOAF的预测价值。方法：采用2023年1月至2024年1月的随访数据，对1581例AMI患者进行回顾性分析。测量p波变量，并根据院内NOAF发生情况对患者进行分组。结果：总体而言，1581例患者中有164例（10.3%）发生NOAF。年龄（61.08±12.02 vs 67.91±11.60,p < 0.01）（25.3% vs 55.5%, p < 0.01）结论：在文献和指南的房颤危险因素中加入p波变量可显著提高NOAF的风险辨别能力。p波变量与AMI后NOAF密切相关。添加这些变量增强了ami后NOAF的预测性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Noninvasive Electrocardiology 医学-心血管系统

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (A.N.E) is an online only journal that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. ANE is the first journal in an evolving subspecialty that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. The publication includes topics related to 12-lead, exercise and high-resolution electrocardiography, arrhythmias, ischemia, repolarization phenomena, heart rate variability, circadian rhythms, bioengineering technology, signal-averaged ECGs, T-wave alternans and automatic external defibrillation. ANE publishes peer-reviewed articles of interest to clinicians and researchers in the field of noninvasive electrocardiology. Original research, clinical studies, state-of-the-art reviews, case reports, technical notes, and letters to the editors will be published to meet future demands in this field.