Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent experience

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-02-01 DOI:10.1016/j.pdpdt.2024.104447

Gennady Meerovich , Evgeniya Kogan , Igor Romanishkin , Nikolay Zharkov , Sofiya Avraamova , Elena Shchelokova , Ekaterina Akhlyustina , Marina Strakhovskaya , Irina Meerovich , Sofya Demura , Irina Tiganova , Yulia Romanova , Zhi-Long Chen , Igor Reshetov

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引用次数: 0

Abstract

The problem of treating cancer patients with lung cancer has become more difficult due to the SARS-CoV-2 viral infection and concomitant bacterial lesions. The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the destruction of cancer stem cells), SARS-CoV-2 coronavirus infection, Gram-positive and Gram-negative bacteria, including those that can cause pneumonia. Therefore, the photodynamic approach using such photosensitizers is promising for the development of an effective treatment method for patients with lung cancer, including those with SARS-CoV-2 infection and bacterial complications.

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利用多阳离子光敏剂进行光动力疗法治疗 SARS-CoV-2 感染和细菌并发症肺癌患者的潜力：我们最近的经验。

由于SARS-CoV-2病毒感染和伴随的细菌病变，癌症患者合并肺癌的治疗问题变得更加困难。分析表明，长波长多阳离子光敏剂的光动力效应抑制肿瘤过程（包括破坏癌症干细胞）、SARS-CoV-2冠状病毒感染、革兰氏阳性和革兰氏阴性细菌，包括可引起肺炎的细菌。因此，使用这种光敏剂的光动力学方法有望为肺癌患者，包括SARS-CoV-2感染和细菌并发症患者提供有效的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.