Axillary lymph node management strategies in cN + breast cancer patients after neoadjuvant chemotherapy.

IF 2.8 3区医学 Q2 ONCOLOGY

Clinical & Translational Oncology Pub Date : 2024-12-17 DOI:10.1007/s12094-024-03817-6

Min Gao, Xiaoxi Chen, Ling Xu

引用次数: 0

Abstract

With the widespread use of neoadjuvant chemotherapy (NAC), the optimal management strategy for axillary lymph nodes following chemotherapy has become a hot topic of discussion. For patients with clinically positive axillary lymph nodes (cN +) (defined as axillary lymph nodes confirmed positive by pathology before NAC), axillary lymph node dissection (ALND) remains the current standard treatment. However, there is still no consensus on whether sentinel lymph node biopsy (SLNB) and other local axillary treatments following NAC can safely replace ALND to reduce injury and complications. This article provides a narrative review of strategies for managing axillary lymph nodes in this patient population.

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新辅助化疗后 cN + 乳腺癌患者的腋窝淋巴结管理策略。

随着新辅助化疗（NAC）的广泛应用，化疗后腋窝淋巴结的最佳治疗策略已成为一个热门话题。对于腋窝淋巴结临床阳性（cN +）（指新辅助化疗前病理证实为阳性的腋窝淋巴结）的患者，腋窝淋巴结清扫术（ALND）仍是目前的标准治疗方法。然而，前哨淋巴结活检（SLNB）和 NAC 后的其他腋窝局部治疗能否安全地取代 ALND 以减少损伤和并发症，目前仍未达成共识。本文对此类患者的腋窝淋巴结管理策略进行了叙述性综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical & Translational Oncology 医学-肿瘤学

CiteScore

6.20

自引率

2.90%

发文量

240

审稿时长

1 months

期刊介绍： Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of new targets for cancer therapy, and new technologies for research and treatment of cancer are the major themes covered by the educational series. Full research articles on a broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.