Prospective Analytical Case-Control Study of COVID-19 Positive Versus Negative Patients for Subclinical Placental Dysfunction.

Q3 Medicine

Iranian Journal of Pathology Pub Date : 2024-01-01 Epub Date: 2024-07-24 DOI:10.30699/IJP.2024.2017566.3225

Poojan Dogra Marwaha, Jyoti Bala, Suchi Sharma, Asmita Kaundal, Neha Chauhan

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Abstract

Background & objective: Placenta provides nutrition and protection from various infections and toxins to the baby while they are in the mother's womb. The present study was done to see the effects of coronavirus infection on the placenta of infected mothers and the final pregnancy outcome.

Methods: A total of 50 antenatal women (25 infected with coronavirus and 25 uninfected women) were enrolled and their placentae were examined for any significant histopathological changes. These changes were then correlated with the final pregnancy outcome.

Results: A significant number of placentae from infected mothers demonstrated features of maternal (54%) and fetal malperfusion (76%). However, no significant adverse pregnancy outcome was noted.

Conclusion: Increased rates of maternal malperfusion, and fetal malperfusion may be seen in placentae from infected women. However, these changes may not progress to any adverse fetal outcomes.

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COVID-19阳性与阴性患者亚临床胎盘功能障碍的前瞻性分析病例对照研究

背景和目的：胎盘为胎儿在母体内提供营养，并保护胎儿免受各种感染和毒素的侵害。本研究旨在了解冠状病毒感染对受感染母亲胎盘的影响以及最终的妊娠结果：方法：共招募了 50 名产前妇女（25 名感染冠状病毒的妇女和 25 名未受感染的妇女），对她们的胎盘进行检查，以确定是否存在明显的组织病理学变化。然后将这些变化与最终的妊娠结果联系起来：结果：大量受感染母亲的胎盘表现出母体（54%）和胎儿（76%）灌注不良的特征。结论：受感染母亲的胎盘中，母体（54%）和胎儿（76%）有灌注不良的特征，但没有发现明显的不良妊娠结局：结论：受感染妇女的胎盘可能会出现母体灌注不良和胎儿灌注不良的情况。结论：受感染妇女的胎盘可能会增加母体灌注不良和胎儿灌注不良的比例，但这些变化可能不会对胎儿造成任何不良后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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