The effect of heated tobacco products on metabolic syndrome: A cohort study.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI:10.18332/tid/194490

Yongho Jee, Sang Yop Shin, Mikyung Ryu, Jonathan M Samet

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引用次数: 0

Abstract

Introduction: Evidence concerning the health effects of using heated tobacco products is needed. The aim of the present study is to investigate the effects of conventional cigarettes (CCs), electronic vaping cigarettes (EVCs), and heated tobacco products (HTPs) on the development of metabolic syndrome.

Methods: We conducted a cohort study in South Korea using data from the Korea Medical Institute. The study included 183870 people who visited the Korea Medical Institute, responded to a smoking status questionnaire in 2019, and were followed up in 2020 - ever and current use of CCs, EVCs, and HTPs. We defined the main outcome as incident metabolic syndrome among participants with at least two health checkups separated by a follow-up period of at least a year.

Results: The association of using HTPs with risk for metabolic syndrome was estimated after controlling for age, sex, exercise, drinking history, and smoking regular cigarettes and using EVCs, with the Cox proportional hazards model. The risk of incident metabolic syndrome was increased by 68% (HR=1.68; 95% CI: 1.25-2.26) for current HTP users compared to never users. Among HTP users who did not currently smoke conventional cigarettes, the risk was doubled (HR=2.17; 95% CI: 1.31-3.62) when their smoking duration was ≥3 years. The risk of metabolic syndrome increased by 33% (HR=1.33; CI: 1.18-1.49) among HTP users who used them more than 16 times a day. The use of HTP was found to increase the risk of developing metabolic syndrome, with a particularly elevated risk observed among those who used HTPs for more than three years. The risk was higher than that observed in conventional cigarette users.

Conclusions: Our findings indicate that HTP use poses comparable risks in relation to metabolic syndrome development.

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介绍：使用加热烟草制品对健康的影响需要证据。本研究旨在调查传统香烟（CC）、电子烟（EVC）和加热烟草制品（HTP）对代谢综合征发病的影响：我们利用韩国医学研究院的数据在韩国开展了一项队列研究。该研究纳入了183870名曾在韩国医学研究院就诊、在2019年回答吸烟状况问卷并在2020年接受随访的人--他们曾经和目前使用CC、EVC和HTP。我们将主要结果定义为：在至少两次健康检查之间，随访时间至少间隔一年的参与者中，发生代谢综合征：在控制了年龄、性别、运动、饮酒史、经常吸烟和使用 EVC 后，使用 HTPs 与代谢综合征风险的关系通过 Cox 比例危险模型进行了估计。与从未使用过 HTP 的人群相比，目前使用 HTP 的人群发生代谢综合征的风险增加了 68%（HR=1.68；95% CI：1.25-2.26）。在目前不吸食传统香烟的 HTP 使用者中，当吸烟时间≥3 年时，风险增加一倍（HR=2.17；95% CI：1.31-3.62）。每天使用 HTP 超过 16 次的人患代谢综合征的风险增加了 33%（HR=1.33；CI：1.18-1.49）。研究发现，使用 HTP 会增加患代谢综合征的风险，使用 HTP 超过三年的人患代谢综合征的风险尤其高。这种风险高于传统香烟使用者：我们的研究结果表明，使用 HTP 会对代谢综合征的发生带来类似的风险。

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.