CATALYZE: A DEEP LEARNING APPROCH FOR CATARACT ASSESSEMENT AND GRADING ON SS-OCT ANTERION IMAGES.

IF 2.6 3区医学 Q2 OPHTHALMOLOGY

Journal of cataract and refractive surgery Pub Date : 2024-12-16 DOI:10.1097/j.jcrs.0000000000001598

Christophe Panthier, Pierre Zeboulon, Helene Rouger, Jacques Bijon, Damien Gatinel

{"title":"CATALYZE: A DEEP LEARNING APPROCH FOR CATARACT ASSESSEMENT AND GRADING ON SS-OCT ANTERION IMAGES.","authors":"Christophe Panthier, Pierre Zeboulon, Helene Rouger, Jacques Bijon, Damien Gatinel","doi":"10.1097/j.jcrs.0000000000001598","DOIUrl":null,"url":null,"abstract":"Purpose: To assess an new objective deep learning model cataract grading method based on Swept-Source Optical Coherence Tomography (SS-OCT) scans provided by the Anterion® (Heidelberg, Germany).Setting: Single centre study at the Rothschild Foundation, Paris, France.Design: Prospective cross-sectional study.Methods: All patients consulting for cataract evaluation and consenting to study participation were included. History of previous ocular surgery, cornea or retina disorders, and ocular dryness were exclusion criteria. Our CATALYZE pipeline was applied to Anterion® image providing layer-wise cataract metrics and an overall Clinical Significance Index of cataract (CSI). Ocular scatter index (OSI) was also measured with a double-pass aberrometer (OQAS®), and compared to our CSI.Results: Five hundred forty eight eyes were included, 331 in the development set (48 with cataract and 283 controls) and 217 in the validation set (85 with cataract and 132 controls) of 315 patients aged 19-85 years (mean ± SD: 50 ± 21 years). The CSI correlated with the OSI (r2 = 0.87, P <0.01). CSI area under the ROC curve (AUROC) was comparable to OSI AUROC (0.985 vs 0.981 respectively, P>0.05) with 95% sensitivity and 95% specificity.Conclusions: Our deep learning pipeline CATALYZE based on Anterion® SS-OCT is a reliable and comprehensive objective cataract grading method.","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cataract and refractive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/j.jcrs.0000000000001598","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To assess an new objective deep learning model cataract grading method based on Swept-Source Optical Coherence Tomography (SS-OCT) scans provided by the Anterion® (Heidelberg, Germany).

Setting: Single centre study at the Rothschild Foundation, Paris, France.

Design: Prospective cross-sectional study.

Methods: All patients consulting for cataract evaluation and consenting to study participation were included. History of previous ocular surgery, cornea or retina disorders, and ocular dryness were exclusion criteria. Our CATALYZE pipeline was applied to Anterion® image providing layer-wise cataract metrics and an overall Clinical Significance Index of cataract (CSI). Ocular scatter index (OSI) was also measured with a double-pass aberrometer (OQAS®), and compared to our CSI.

Results: Five hundred forty eight eyes were included, 331 in the development set (48 with cataract and 283 controls) and 217 in the validation set (85 with cataract and 132 controls) of 315 patients aged 19-85 years (mean ± SD: 50 ± 21 years). The CSI correlated with the OSI (r2 = 0.87, P <0.01). CSI area under the ROC curve (AUROC) was comparable to OSI AUROC (0.985 vs 0.981 respectively, P>0.05) with 95% sensitivity and 95% specificity.

Conclusions: Our deep learning pipeline CATALYZE based on Anterion® SS-OCT is a reliable and comprehensive objective cataract grading method.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

$Journal of cataract and refractive surgery$

Journal of cataract and refractive surgery 医学-外科

CiteScore

5.60

自引率

14.30%

发文量

259

审稿时长

8.5 weeks

期刊介绍： The Journal of Cataract & Refractive Surgery (JCRS), a preeminent peer-reviewed monthly ophthalmology publication, is the official journal of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS). JCRS publishes high quality articles on all aspects of anterior segment surgery. In addition to original clinical studies, the journal features a consultation section, practical techniques, important cases, and reviews as well as basic science articles.