Heat acclimation induces hypothalamic temperature sensitivity that promotes heat tolerance

IF 21.2 1区医学 Q1 NEUROSCIENCES

Nature neuroscience Pub Date : 2024-12-17 DOI:10.1038/s41593-024-01835-9

引用次数: 0

Abstract

After long-term heat exposure, a discrete group of hypothalamic neurons in the anterior ventromedial preoptic area become hyperactive and acquire temperature sensitivity. This reversible plasticity mechanism renders mice heat tolerant, meaning they can keep their body temperature within physiological limits when ambient temperatures are high.

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热适应诱导下丘脑温度敏感性，促进耐热性

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来源期刊

Nature neuroscience 医学-神经科学

CiteScore

38.60

自引率

1.20%

发文量

212

审稿时长

1 months

期刊介绍： Nature Neuroscience, a multidisciplinary journal, publishes papers of the utmost quality and significance across all realms of neuroscience. The editors welcome contributions spanning molecular, cellular, systems, and cognitive neuroscience, along with psychophysics, computational modeling, and nervous system disorders. While no area is off-limits, studies offering fundamental insights into nervous system function receive priority. The journal offers high visibility to both readers and authors, fostering interdisciplinary communication and accessibility to a broad audience. It maintains high standards of copy editing and production, rigorous peer review, rapid publication, and operates independently from academic societies and other vested interests. In addition to primary research, Nature Neuroscience features news and views, reviews, editorials, commentaries, perspectives, book reviews, and correspondence, aiming to serve as the voice of the global neuroscience community.