Myelodysplastic syndromes among atomic bomb survivors in Nagasaki: similarities to and differences from de novo and therapy-related cases.

IF 1.9 4区医学 Q2 BIOLOGY

Journal of Radiation Research Pub Date : 2024-12-15 DOI:10.1093/jrr/rrae003

Koji Ando, Yasushi Miyazaki

引用次数: 0

Abstract

Epidemiological studies for atomic bomb (A-bomb) survivors clearly demonstrated that A-bomb radiation increased the risk of hematological neoplasms, such as acute and chronic leukemia, and myelodysplastic syndromes (MDS) among survivors. Several studies on MDS among survivors investigated its characteristics, and it seems that MDS among survivors has different features from those seen in de novo MDS and therapy-related MDS. In this short review, we describe the differences of clinical features, chromosomal alterations and genome aberrations among them.

查看原文本刊更多论文

长崎原子弹爆炸幸存者骨髓增生异常综合征：与新发病例和治疗相关病例的异同。

对原子弹幸存者的流行病学研究清楚地表明，原子弹辐射增加了幸存者患血液肿瘤（如急性和慢性白血病）和骨髓增生异常综合征（MDS）的风险。一些关于幸存者MDS的研究调查了其特征，似乎幸存者MDS与新生MDS和治疗相关MDS具有不同的特征。在这篇简短的综述中，我们描述了它们的临床特征、染色体改变和基因组畸变的差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Radiation Research 医学-核医学

CiteScore

3.60

自引率

5.00%

发文量

审稿时长

4-8 weeks

期刊介绍： The Journal of Radiation Research (JRR) is an official journal of The Japanese Radiation Research Society (JRRS), and the Japanese Society for Radiation Oncology (JASTRO). Since its launch in 1960 as the official journal of the JRRS, the journal has published scientific articles in radiation science in biology, chemistry, physics, epidemiology, and environmental sciences. JRR broadened its scope to include oncology in 2009, when JASTRO partnered with the JRRS to publish the journal. Articles considered fall into two broad categories: Oncology & Medicine - including all aspects of research with patients that impacts on the treatment of cancer using radiation. Papers which cover related radiation therapies, radiation dosimetry, and those describing the basis for treatment methods including techniques, are also welcomed. Clinical case reports are not acceptable. Radiation Research - basic science studies of radiation effects on livings in the area of physics, chemistry, biology, epidemiology and environmental sciences. Please be advised that JRR does not accept any papers of pure physics or chemistry. The journal is bimonthly, and is edited and published by the JRR Editorial Committee.