Wide-field indocyanine green fluorescein angiography findings in inferior posterior staphyloma.

IF 2.4 3区 医学 Q2 OPHTHALMOLOGY
Koichi Yokoi, Michiyuki Saito, Mizuho Mitamura, Susumu Ishida
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引用次数: 0

Abstract

Inferior posterior staphyloma (IPS) is a rare disease typically associated with tilted disc syndrome, characterized by posterior staphyloma within the inferior fundus, without pathological myopia. Subretinal fluid (SRF) occurs in about 30-40% of IPS cases. This study investigated choroidal circulation and morphological changes in IPS using widefield indocyanine green angiography (ICGA). The study included 14 eyes of 8 Japanese patients (mean age: 65.1 years) with treatment-naïve IPS and utilized ICGA and optical coherence tomography. Exclusion criteria were high myopia, macular diseases, prior treatments, and contrast media allergy. The main ICGA findings were a downward shift of the watershed (85.7% of eyes), asymmetric dilated vortex vein (ADVV) (85.7%), anastomosis between the superior and inferior choroidal veins (57.1%), and delayed choroidal filling (100%). SRF was present in seven eyes. No statistical differences were found in the ratio of downward shift, ADVV, or delayed filling between eyes with or without SRF. However, anastomosis was significantly higher in eyes without SRF. The study concluded that IPS shows high prevalence of watershed shift, ADVV, anastomosis, and choroidal filling delay, with anastomosis potentially resolving SRF by reducing choroidal blood flow congestion, similar to pachychoroid spectrum diseases. KEY MESSAGES : WHAT IS KNOWN : Inferior posterior staphyloma (IPS) sometimes occurs subretinal fluid (SRF), however the mechanism of its appearance and disappearence is unknown. WHAT IS NEW : Indocyanine green angiography (ICGA) findings in IPS showed the downward shift in the watershed, asymmetric dilated vortex vein (ADVV), and choroidal filling delay, which was also found in pachychoroid spectrum diseases (PDS). Anastomosis between the superior and inferior choroidal veins across watershed contributes to the resolution of SRF in that it reduces the overload as the anastomosis progresses. We suggest that the mechanism for the appearance and disappearance of SRF in IPS may be due to the same mechanism that an imbalance in macular choroidal blood flow and localized hyperperfusion as in PDS.

下后葡萄胎的宽视野吲哚菁绿荧光素血管造影检查结果。
下眼底后葡萄胎(IPS)是一种罕见的疾病,通常与椎间盘倾斜综合征有关,其特点是下眼底后葡萄胎,但无病理性近视。约 30-40% 的 IPS 病例会出现视网膜下积液(SRF)。本研究使用宽视野吲哚青绿血管造影术(ICGA)研究了 IPS 的脉络膜循环和形态变化。该研究纳入了 8 名日本 IPS 患者(平均年龄 65.1 岁)的 14 只眼睛,他们都是未经治疗的 IPS 患者,研究采用了 ICGA 和光学相干断层扫描技术。排除标准为高度近视、黄斑疾病、曾接受过治疗和造影剂过敏。ICGA 的主要发现是分水岭下移(85.7% 的眼睛)、不对称扩张涡状静脉(ADVV)(85.7%)、脉络膜上静脉和脉络膜下静脉吻合(57.1%)以及脉络膜充盈延迟(100%)。7只眼睛存在SRF。有无 SRF 的双眼在下移比例、ADVV 或延迟充盈方面没有统计学差异。但是,没有 SRF 的眼睛吻合率明显更高。研究得出结论,IPS显示出较高的分水岭移位、ADVV、吻合和脉络膜充盈延迟发生率,吻合可能通过减少脉络膜血流充血来解决SRF问题,这与脉络膜睫状体频谱疾病类似。关键信息已知:后葡萄膜下瘤(IPS)有时会出现视网膜下积液(SRF),但其出现和消失的机制尚不清楚。新发现:IPS 的吲哚青绿血管造影(ICGA)结果显示分水岭下移、不对称扩张涡状静脉(ADVV)和脉络膜充盈延迟,这在蛛网膜谱系疾病(PDS)中也有发现。上脉络膜静脉和下脉络膜静脉之间的跨分水岭吻合有助于解决 SRF 问题,因为随着吻合的进行,超负荷会减轻。我们认为,IPS 中 SRF 出现和消失的机制可能与 PDS 中黄斑脉络膜血流失衡和局部高灌注的机制相同。
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来源期刊
CiteScore
5.40
自引率
7.40%
发文量
398
审稿时长
3 months
期刊介绍: Graefe''s Archive for Clinical and Experimental Ophthalmology is a distinguished international journal that presents original clinical reports and clini-cally relevant experimental studies. Founded in 1854 by Albrecht von Graefe to serve as a source of useful clinical information and a stimulus for discussion, the journal has published articles by leading ophthalmologists and vision research scientists for more than a century. With peer review by an international Editorial Board and prompt English-language publication, Graefe''s Archive provides rapid dissemination of clinical and clinically related experimental information.
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