Silver mean sequence in extended depth of focus intraocular lenses: a comparative study of kinoform and stepwise designs.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Biomedical optics express Pub Date : 2024-11-26 eCollection Date: 2024-12-01 DOI:10.1364/BOE.540754
Anabel Martínez-Espert, Vicente Ferrando, Adrián Garmendía-Martínez, Francisco M Muñoz-Pérez, Juan A Monsoriu, Walter D Furlan
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Abstract

In this work, we present two new multifocal intraocular lens (MIOL) designs, both based on the silver mean kinoform diffractive lens. We demonstrate that a single aperiodic diffractive profile can be used to create two different MIOLs: one with a kinoform structure and the other with a stepwise profile. Quantitative assessment of the designs was carried out using the through focus modulation transfer function and the area under the modulation transfer function for the prediction of their visual performance. Our results show that both designs exhibit nearly identical optical performance at the design wavelength (λ = 550 nm), though their intrinsic longitudinal chromatic aberration differs significantly. Given that diffractive extended depth of focus (EDoF) intraocular lenses are prone to image degradation due to dysphotopic phenomena, we also compared the halos generated by these two designs and found notable differences in their behavior. Furthermore, under photopic conditions, the proposed lens designs demonstrated the potential to achieve visual acuity values of 0.2 logMAR or better across a vergence range from approximately 0 to 2 D. Finally, to qualitatively assess the behavior of the MIOLs, an objective experimental evaluation was conducted using an adaptive optics visual simulator in a model eye. Experimental results align with the quantitative assessment of the proposed designs.

扩展焦深眼内透镜中的银平均序列:动力学形态和分步设计的比较研究。
在这项研究中,我们提出了两种新的多焦点眼内透镜(MIOL)设计,这两种设计都是基于银平均基诺形衍射透镜。我们证明了单一的非周期性衍射轮廓可用于制造两种不同的 MIOL:一种是基诺形结构,另一种是阶梯形轮廓。我们使用通焦调制传递函数和调制传递函数下面积对这些设计进行了定量评估,以预测它们的视觉性能。结果表明,这两种设计在设计波长(λ = 550 nm)下的光学性能几乎相同,但其内在纵向色差差异很大。鉴于衍射型延展焦深(EDoF)眼内透镜容易因视差现象而导致图像质量下降,我们还比较了这两种设计所产生的光晕,发现它们在行为上存在明显差异。此外,在光视条件下,所提出的镜片设计有可能在大约 0 到 2 D 的辐辏范围内实现 0.2 logMAR 或更高的视力值。最后,为了对 MIOL 的行为进行定性评估,我们在模型眼上使用自适应光学视觉模拟器进行了客观的实验评估。实验结果与建议设计的定量评估结果一致。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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