Risk of Sarcopenia Following Long-Term Statin Use in Community-Dwelling Middle-Aged and Older Adults in Japan

IF 8.9 1区医学

Journal of Cachexia, Sarcopenia and Muscle Pub Date : 2024-12-16 DOI:10.1002/jcsm.13660

Shih-Tsung Huang, Rei Otsuka, Yukiko Nishita, Lin-Chieh Meng, Fei-Yuan Hsiao, Hiroshi Shimokata, Liang-Kung Chen, Hidenori Arai

引用次数: 0

Abstract

Inconsistent results have been reported concerning the association between statin administration and muscle health, specifically its potential to increase the risk of sarcopenia. Given the widespread long-term use of statins among the elderly population, the exploration of this association remains a crucial yet insufficiently examined matter. This study aimed to assess the association between the prolonged administration of statins and the risk of sarcopenia, diminished muscle strength, reduced skeletal muscle mass and impaired physical performance.

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日本社区中老年人长期服用他汀类药物后患肌少症的风险

关于他汀类药物与肌肉健康之间的关系，特别是其可能增加肌肉减少症的风险，已有不一致的结果报告。鉴于他汀类药物在老年人群中的长期广泛使用，探索这种关联仍然是一个至关重要但尚未充分研究的问题。本研究旨在评估长期服用他汀类药物与肌肉减少、肌肉力量减弱、骨骼肌质量减少和身体机能受损风险之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cachexia, Sarcopenia and Muscle Medicine-Orthopedics and Sports Medicine

自引率

12.40%

发文量

期刊介绍： The Journal of Cachexia, Sarcopenia, and Muscle is a prestigious, peer-reviewed international publication committed to disseminating research and clinical insights pertaining to cachexia, sarcopenia, body composition, and the physiological and pathophysiological alterations occurring throughout the lifespan and in various illnesses across the spectrum of life sciences. This journal serves as a valuable resource for physicians, biochemists, biologists, dieticians, pharmacologists, and students alike.