Single-pill combination therapy is the standard of care for hypertension, but it is time for the next step: Implementation.

IF 12.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2024-12-13 DOI:10.1016/j.medj.2024.11.010

Jose P Lopez-Lopez, Patricio Lopez-Jaramillo

引用次数: 0

Abstract

The GMRx2 trial¹ in adults with high blood pressure (BP) demonstrated that after 12 weeks, a low-dose single-pill combination of telmisartan, amlodipine, and indapamide significantly reduced BP levels compared to several dual combinations (telmisartan with amlodipine, telmisartan with indapamide, or amlodipine with indapamide). Adverse events did not differ between the groups. This novel therapeutic option could improve high BP control.

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在成人高血压患者中开展的 GMRx2 试验1 表明，12 周后，与几种双药组合（替米沙坦加氨氯地平、替米沙坦加吲达帕胺或氨氯地平加吲达帕胺）相比，低剂量单药组合替米沙坦、氨氯地平和吲达帕胺可显著降低血压水平。各组之间的不良反应没有差异。这种新型疗法可改善高血压控制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

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