Axial elongation in nonpathologic high myopia: Ocular structural changes and glaucoma diagnostic challenges

IF 3.7 3区 医学 Q1 OPHTHALMOLOGY
Kangjie Kong , Xiaoyi Liu , Zige Fang , Jingwen Jiang , Jiaxuan Jiang , Deming Wang , Zefeng Yang , Fengqi Zhou , Evan M. Chen , Jill Liang , Yunhe Song , Fengbin Lin , Kyoko Ohno-Matsui , Jost B. Jonas , Ying Han , Fei Li , Xiulan Zhang , for the Glaucoma Suspects with High Myopia Study Group
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引用次数: 0

Abstract

Axial elongation continues in highly myopic adult eyes, even in the absence of pathologic changes such as posterior staphyloma or chorioretinal atrophy. This ongoing axial elongation leads to structural changes in the macular and peripapillary regions, including chorioretinal thinning, reduced vascular perfusion and optic disc tilting and rotation, among others. These alterations can affect the acquisition and interpretation of optical coherence tomography, optical coherence tomography angiography and fundus photographs, potentially introducing artifacts and diminishing the accuracy of glaucoma diagnosis in highly myopic eyes. In this review, we compared the progression patterns of axial elongation across populations with varying demographic characteristics, genetic and environmental backgrounds and ocular features. We also discussed the implications of axial elongation–induced ocular structural changes for diagnosing glaucoma in nonpathologic high myopia. Finally, we highlighted the prospects for enhancing the diagnostic efficacy of glaucoma in nonpathologic highly myopic populations.
非病理性高度近视的眼轴伸长:眼部结构改变和青光眼诊断挑战。
在高度近视的成人眼睛中,即使没有诸如后葡萄肿或绒毛膜视网膜萎缩等病理改变,轴向伸长仍在继续。这种持续的轴向伸长导致黄斑和乳头周围区域的结构改变,包括脉络膜变薄、血管灌注减少和视盘倾斜和旋转等。这些改变会影响光学相干断层扫描、光学相干断层血管造影和眼底照片的采集和解释,可能会产生伪影,降低高度近视眼睛青光眼诊断的准确性。在这篇综述中,我们比较了不同人口统计学特征、遗传和环境背景以及眼部特征的人群中轴向伸长的进展模式。我们也讨论了眼轴伸长引起的眼部结构变化对非病理性高度近视青光眼的诊断意义。最后,我们强调了在非病理性高度近视人群中提高青光眼诊断效能的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.10
自引率
18.20%
发文量
197
审稿时长
6 weeks
期刊介绍: The Asia-Pacific Journal of Ophthalmology, a bimonthly, peer-reviewed online scientific publication, is an official publication of the Asia-Pacific Academy of Ophthalmology (APAO), a supranational organization which is committed to research, training, learning, publication and knowledge and skill transfers in ophthalmology and visual sciences. The Asia-Pacific Journal of Ophthalmology welcomes review articles on currently hot topics, original, previously unpublished manuscripts describing clinical investigations, clinical observations and clinically relevant laboratory investigations, as well as .perspectives containing personal viewpoints on topics with broad interests. Editorials are published by invitation only. Case reports are generally not considered. The Asia-Pacific Journal of Ophthalmology covers 16 subspecialties and is freely circulated among individual members of the APAO’s member societies, which amounts to a potential readership of over 50,000.
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