How do residential aged care antibiograms compare with other local resistance data?

IF 3.8 3区医学 Q2 INFECTIOUS DISEASES

American journal of infection control Pub Date : 2024-12-11 DOI:10.1016/j.ajic.2024.12.001

Dipti Khatri, Nazanin Falconer, Sonali Coulter, Leonard C Gray, David L Paterson, Christopher Freeman

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引用次数: 0

Abstract

Background: Antibiograms can optimise empirical antibiotic prescribing however they are not readily available for residential aged care facilities (RACFs) in Queensland, Australia. This study aimed to determine whether alternatively available data can be used to approximate resistance patterns for RACFs.

Method: Annual RACF-specific antibiograms were compared with local hospital antibiograms accessed through pathology providers. Additionally, composite antibiograms, of geographically united RACF data, were compared to regional hospital and private pathology RACF antibiograms. Antibiotic susceptibility rates for commonly observed bacteria (Escherichia coli, Klebsiella pneumonia, Enterococcus faecalis, Pseudomonas aeruginosa and Staphylococcus aureus) were compared amongst different antibiograms using Fisher's exact test, with a p-value ≤ 0.05 indicating statistically significant difference. The concordance amongst the antibiograms was described by percentage similarity overall, and for a subset of clinically relevant pathogen-antibiotic pairs (PAPs).

Results: Composite RACF-antibiogram was highly concordant (83-100% similarity) to private pathology RACF data when compared for clinically relevant PAPs. Mixed results were found when individual RACF-specific antibiograms were compared to local hospital all-ages and ≥65years data (50-100% and 67-100% similarity respectively).

Conclusion: Private pathology RACF antibiograms can serve as a proxy indicator of resistance patterns for RACFs. Mixed findings were noted for comparisons with hospital data.

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)