Pineal Gland Activity in Advanced-Stage Pediatric Neuroblastoma Patients on 68 Ga-DOTATATE PET/CT.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-04-01 Epub Date: 2024-12-13 DOI:10.1097/RLU.0000000000005626

Emine Goknur Isik, Dilara Denizmen, Dilşad Fırat Arslan, Duygu Has Simsek, Zeynep Gözde Özkan

引用次数: 0

Abstract

Abstract: Neuroblastoma is the most common malignancy in infants and the most common extracranial solid tumor accounting for approximately 6% of pediatric cancer. Although surgical intervention serves as the primary treatment for early-stage disease, advanced-stage cases necessitate a variety of oncologic therapeutic approaches, including 131 I-MIBG and peptide receptor radionuclide therapy. Herein we report incidental pineal gland activity, represented in 68 Ga-DOTATATE PET/CT (SSTR-PET) in 3 pediatric patients diagnosed with stage 4 neuroblastoma, related to the physiological distribution of radiopharmaceuticals.

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68Ga-DOTATATE PET/CT对晚期小儿神经母细胞瘤患者松果体活性的影响

摘要：神经母细胞瘤是婴儿最常见的恶性肿瘤，也是最常见的颅外实体瘤，约占儿科癌症的6%。虽然手术治疗是早期疾病的主要治疗方法，但晚期病例需要采用多种肿瘤治疗方法，包括 131I-MIBG 和肽受体放射性核素治疗。在此，我们报告了在 3 名确诊为神经母细胞瘤 4 期的儿科患者中，68Ga-DOTATATE PET/CT（SSTR-PET）显示的松果体活动，这与放射性药物的生理分布有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.