CT scoring system for differentiating of sinonasal inverted papilloma and squamous cell carcinoma arising from inverted papilloma.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2024-12-12 DOI:10.1007/s00405-024-09107-9

Miki Umeda, Masashi Kuroki, Hiroki Kato, Hirofumi Shibata, Nansei Yamada, Hiroshi Okuda, Kosuke Terazawa, Ryota Iinuma, Akira Ohkoshi, Shun Wakamori, Ikuho Kojima, Yukio Katori, Masayuki Matsuo, Takenori Ogawa

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引用次数: 0

Abstract

Objective: To distinguish squamous cell carcinoma in inverted papilloma (IP-SCC) from IP, the utility of CT scoring system was investigated.

Methods: We extracted cases histopathologically diagnosed with IP and IP-SCC of the sinonasal cavity from June 2004 to May 2021. Preoperative unenhanced CT images were used to evaluate the presence or absence of bone destruction and erosion: Score 1 = positive for bone destruction and/or erosion; Score 0 = negative for bone destruction and erosion. The CT scores in 10 sites of the sinonasal cavity and their adjacent areas were calculated.

Results: Fifty-six cases of IP and 20 cases of IP-SCC were enrolled in this study. Bone destruction and/or erosion was more frequently observed in IP-SCC than in IP at the sites of the skull base (p = 0.0001), orbital wall (p < 0.0001), maxillary sinus (p < 0.0001), nasal septum (p < 0.0001), inferior nasal concha (p = 0.0046), ethmoid sinus (p < 0.0001), pterygoid process (p = 0.0031), and frontal sinus (p = 0.0009). The total CT scores at the 10 sites for diagnosing IP-SCC had sensitivity and specificity of 70% and 87.5% (AUC: 0.810, p < 0.001); furthermore, those at the eight sites excluding fontanelle and middle nasal concha improved sensitivity and specificity of 75% and 83.9% (optimal threshold of 2, AUC: 0.862, p < 0.001).

Conclusion: The CT scoring system evaluating bone destruction and erosion could accurately differentiate IP-SCC from IP.

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目的为了区分倒置乳头状瘤中的鳞状细胞癌（IP-SCC）和IP，研究了CT评分系统的实用性：我们抽取了 2004 年 6 月至 2021 年 5 月经组织病理学诊断为鼻窦腔 IP 和 IP-SCC 的病例。术前未增强 CT 图像用于评估是否存在骨质破坏和侵蚀：评分 1 = 骨质破坏和/或侵蚀阳性；评分 0 = 骨质破坏和侵蚀阴性。计算鼻窦腔 10 个部位及其邻近区域的 CT 评分：本研究共纳入 56 例 IP 和 20 例 IP-SCC 患者。在颅底（P = 0.0001）、眶壁（P = 0.0001）、眶内壁（P = 0.0001）和眶外壁（P = 0.0001）等部位，IP-SCC 比 IP 更常观察到骨质破坏和/或侵蚀：评估骨质破坏和侵蚀的 CT 评分系统可准确区分 IP-SCC 和 IP。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.