Rehan Karmali, Issam Motairek, Samia Mazumder, Felix Berglund, Lorenzo Braghieri, Astefanos Al-Dalakta, Katherine Singh, Brittany Weber, Allan Klein
{"title":"Non-invasive multimodality imaging and special treatment considerations for pericarditis in pregnancy.","authors":"Rehan Karmali, Issam Motairek, Samia Mazumder, Felix Berglund, Lorenzo Braghieri, Astefanos Al-Dalakta, Katherine Singh, Brittany Weber, Allan Klein","doi":"10.1016/j.amjcard.2024.12.007","DOIUrl":null,"url":null,"abstract":"<p><p>Pericarditis in women who are pregnant or of childbearing age poses a challenge to clinicians. Currently, there are no guidelines regarding the optimal approach for managing pericarditis in pregnancy with regards to selecting the appropriate method of diagnostic imaging or tailoring the treatment regimen to gestational age. Pericarditis in pregnancy may manifest as an autoimmune or autoinflammatory phenotype but the predominant etiology is idiopathic. Transthoracic echocardiography and cardiac magnetic resonance are considered safe, but data is lacking on the use of gadolinium-based contrast agents. Shared-decision making is paramount to balance risks and benefits of radiation and contrast exposure to the mother and fetus. The safety profile of treatment options differs at each time-interval from preconception to the three trimesters and postpartum phase. A multidisciplinary approach using imaging guidance can improve outcomes in pregnant patients with pericarditis. Further studies are needed to ascertain the safety of Interleukin-1 blocking agents in pregnancy.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.amjcard.2024.12.007","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Pericarditis in women who are pregnant or of childbearing age poses a challenge to clinicians. Currently, there are no guidelines regarding the optimal approach for managing pericarditis in pregnancy with regards to selecting the appropriate method of diagnostic imaging or tailoring the treatment regimen to gestational age. Pericarditis in pregnancy may manifest as an autoimmune or autoinflammatory phenotype but the predominant etiology is idiopathic. Transthoracic echocardiography and cardiac magnetic resonance are considered safe, but data is lacking on the use of gadolinium-based contrast agents. Shared-decision making is paramount to balance risks and benefits of radiation and contrast exposure to the mother and fetus. The safety profile of treatment options differs at each time-interval from preconception to the three trimesters and postpartum phase. A multidisciplinary approach using imaging guidance can improve outcomes in pregnant patients with pericarditis. Further studies are needed to ascertain the safety of Interleukin-1 blocking agents in pregnancy.
期刊介绍:
Published 24 times a year, The American Journal of Cardiology® is an independent journal designed for cardiovascular disease specialists and internists with a subspecialty in cardiology throughout the world. AJC is an independent, scientific, peer-reviewed journal of original articles that focus on the practical, clinical approach to the diagnosis and treatment of cardiovascular disease. AJC has one of the fastest acceptance to publication times in Cardiology. Features report on systemic hypertension, methodology, drugs, pacing, arrhythmia, preventive cardiology, congestive heart failure, valvular heart disease, congenital heart disease, and cardiomyopathy. Also included are editorials, readers'' comments, and symposia.