Stretchable Multimodal Photonic Sensor for Wearable Multiparameter Health Monitoring

IF 27.4 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Jingjing Guo, Jialin Tuo, Jiangtao Sun, Zhuozhou Li, Xiaoyan Guo, Yanyan Chen, Rong Cai, Jing Zhong, Lijun Xu
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Abstract

Stretchable sensors that can conformally interface with the skins for wearable and real-time monitoring of skin deformations, temperature, and sweat biomarkers offer critical insights for early disease prediction and diagnosis. Integration of multiple modalities in a single stretchable sensor to simultaneously detect these stimuli would provide a more comprehensive understanding of human physiology, which, however, has yet to be achieved. Here, this work reports, for the first time, a stretchable multimodal photonic sensor capable of simultaneously detecting and discriminating strain deformations, temperature, and sweat pH. The multimodal sensing abilities are enabled by realization of multiple sensing mechanisms in a hydrogel-coated polydimethylsiloxane (PDMS) optical fiber (HPOF), featured with high flexibility, stretchability, and biocompatibility. The integrated mechanisms are designed to operate at distinct wavelengths to facilitate stimuli decoupling and employ a ratiometric detection strategy for improved robustness and accuracy. To simplify sensor interrogation, spectrally-resolved multiband emissions are generated upon the excitation of a single-wavelength laser, utilizing upconversion luminescence (UCL) and radiative energy transfer (RET) processes. As proof of concept, this work demonstrates the feasibility of simultaneous monitoring of the heartbeat, respiration, body temperature, and sweat pH of a person in real-time, with only a single sensor.

Abstract Image

Abstract Image

用于可穿戴多参数健康监测的可拉伸多模态光子传感器
可拉伸传感器可以与皮肤进行保形接口,用于可穿戴和实时监测皮肤变形,温度和汗液生物标志物,为早期疾病预测和诊断提供关键见解。在单个可拉伸传感器中集成多种模式,同时检测这些刺激,将提供对人体生理学更全面的理解,然而,这一点尚未实现。本文首次报道了一种能够同时检测和识别应变变形、温度和汗液ph的可拉伸多模态光子传感器。这种多模态传感能力是通过在具有高柔韧性、可拉伸性和生物相容性的水凝胶包被聚二甲基硅氧烷(PDMS)光纤(HPOF)中实现多种传感机制而实现的。集成的机制被设计为在不同的波长下工作,以促进刺激解耦,并采用比例检测策略来提高鲁棒性和准确性。为了简化传感器探测,利用上转换发光(UCL)和辐射能量转移(RET)过程,在单波长激光激发下产生光谱分辨多波段发射。作为概念验证,这项工作证明了同时监测一个人的心跳、呼吸、体温和汗液pH值的可行性,只需一个传感器。
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来源期刊
Advanced Materials
Advanced Materials 工程技术-材料科学:综合
CiteScore
43.00
自引率
4.10%
发文量
2182
审稿时长
2 months
期刊介绍: Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.
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