Long-term Effects of COVID-19 on Sleep Patterns

Abstract

Objective: To examine the long-term impact of Coronavirus disease-2019 (COVID-19) on sleep patterns and the prevalence of sleep disorders and to increase public health awareness of long-term COVID-19.

Material and methods: Using the Massachusetts General Brigham Research Patient Data Registry, Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) positive patients were surveyed about their sleep patterns before and after the viral infection. Information related to comorbid conditions and medications was obtained through chart review.

Results: Two hundred and forty-six completed surveys were analyzed. Average age was 53.3±16.3 years, and they were predominantly non-hispanic white (84.1%) and female (74.3%). The mean body mass index (kg/m²) was 29.9±6.9, and a greater proportion were non-smokers (63.2%). After COVID-19, there was an increase in the percentage of participants reporting difficulty initiating (39±49% vs. 31±46% prior to COVID-19 infection P = 0.01). Similarly, the participants reported difficulty in maintaining sleep after COVID infection (57% vs. 43% prior to infection P < 0.001). Additionally, there was an increase in the use of sleep aids (30% vs. 24% before the infection P = 0.003). The participants also reported a decrease in feeling rested and an increase in the need for napping (58% vs. 36%, P < 0.0001) and (27% vs. 40%, P < 0.0001) respectively. The sleep symptoms persisted beyond 12 months in 28% of the participants.

Conclusion: SARS-CoV-2 infection had negative effects on sleep, and a significant proportion of adults experienced insomnia and daytime sleepiness beyond 12 months after recovering from the initial infection.