The productivity burden of breast cancer in Australia

IF 2.4 3区医学 Q3 ONCOLOGY

Cancer Epidemiology Pub Date : 2025-02-01 DOI:10.1016/j.canep.2024.102726

Melanie Lloyd , Divya Bassi , Ella Zomer , Zanfina Ademi

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引用次数: 0

Abstract

Purpose

Breast cancer exerts a considerable burden on an individual’s health, but also impacts society more broadly through lost work productivity. This study aimed to measure the quality of life and productivity burden among Australian females of working age diagnosed with breast cancer in 2022.

Methods

A Markov lifetable model was simulated twice; the initial simulation followed the progression of Australian females diagnosed with breast cancer in 2022 using current population incidence rates, whilst the second simulation hypothetically assumed there were no females living with breast cancer. The difference in the number of life years lived, quality-adjusted life years (QALYs) and productivity-adjusted life years (PALYs) between the two simulations was estimated. All model inputs were derived from previously published sources. Financial costs attributable to each PALY were estimated utilising the total gross domestic product (GDP) for each equivalent full-time worker in Australia (2022 prices) and in scenario analysis using the human capital approach in terms of wage loss, with discounting of 5 % applied.

Results

Over a ten-year period from 2022 to 2031, it is predicted that breast cancer will result in the loss of 4286 years of life lived and 15,597 QALYs. It is also predicted that 16,403 PALYs will be lost, equating to AU$3.26 billion in lost GDP. Results remain robust, showing limited sensitivity to changes in the inputs.

Conclusion

Breast cancer significantly impacts the health and economic welfare of Australian females of working age. Funding initiatives and programs which accelerate recovery and integration back into the workforce are likely to be economically beneficial.

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澳大利亚乳腺癌的生产力负担。

目的：乳腺癌对个人健康造成相当大的负担，但也通过丧失工作效率更广泛地影响社会。这项研究旨在衡量2022年被诊断患有乳腺癌的澳大利亚工作年龄女性的生活质量和生产力负担。方法：对马尔可夫生命表模型进行两次模拟；最初的模拟使用当前的人口发病率跟踪了2022年被诊断患有乳腺癌的澳大利亚女性的进展，而第二次模拟假设没有女性患有乳腺癌。估计了两种模拟之间的生命年数、质量调整生命年（QALYs）和生产力调整生命年（PALYs）的差异。所有的模型输入都来自先前发布的来源。根据澳大利亚每个同等全职工人的国内生产总值（GDP）（2022年价格）估算每个PALY的财务成本，并在情景分析中使用人力资本方法进行工资损失，折扣率为5% %。结果：在2022年至2031年的10年期间，预计乳腺癌将导致4286年的寿命损失和15,597年的QALYs。预计还将损失16,403个PALYs，相当于损失32.6亿澳元的GDP。结果仍然稳健，显示有限的敏感性在输入的变化。结论：乳腺癌显著影响澳大利亚劳动年龄女性的健康和经济福利。资助加速恢复和重新融入劳动力的举措和计划可能在经济上有益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Epidemiology 医学-肿瘤学

CiteScore

4.50

自引率

3.80%

发文量

200

审稿时长

39 days

期刊介绍： Cancer Epidemiology is dedicated to increasing understanding about cancer causes, prevention and control. The scope of the journal embraces all aspects of cancer epidemiology including: • Descriptive epidemiology • Studies of risk factors for disease initiation, development and prognosis • Screening and early detection • Prevention and control • Methodological issues The journal publishes original research articles (full length and short reports), systematic reviews and meta-analyses, editorials, commentaries and letters to the editor commenting on previously published research.