{"title":"Construction and synthesis of NiCo<sub>2</sub>O<sub>4</sub>nanozyme for enhanced antibacterial performance.","authors":"Luchen Zhang, Shuanglong Wang, Ainong Fang, Pengcheng Hu, Yanhui Zhao, Xiaona Sun, Xiaopeng Lan, Yuan Liu, Chunzhao Liu, Chunlei Liu","doi":"10.1088/1361-6528/ad9d49","DOIUrl":null,"url":null,"abstract":"<p><p>Developing effective and low-cost enzyme-like nanomaterials to kill bacteria is vital for human health. Herein, nanorod-assembled NiCo<sub>2</sub>O<sub>4</sub>microspheres were prepared though a facile hydrothermal method, andshowed highly enhanced peroxidase-like activity compared to pure Co<sub>3</sub>O<sub>4</sub>due to its large surface area and abundant active sites. The NiCo<sub>2</sub>O<sub>4</sub>possess the ability to catalyze H<sub>2</sub>O<sub>2</sub>to generate large amounts of •O<sup>2-</sup>, which can be used for bacteriostatic applications. In particular, the antibacterial system combining the spiky NiCo<sub>2</sub>O<sub>4</sub>particles and a low concentration of H<sub>2</sub>O<sub>2</sub>(100<i>μ</i>M) exhibits an excellent bacteriostatic efficiency against both<i>Escherichia coli</i>(94.44%) and<i>Staphylococcus aureus</i>(93.45%).</p>","PeriodicalId":19035,"journal":{"name":"Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotechnology","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1088/1361-6528/ad9d49","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Developing effective and low-cost enzyme-like nanomaterials to kill bacteria is vital for human health. Herein, nanorod-assembled NiCo2O4microspheres were prepared though a facile hydrothermal method, andshowed highly enhanced peroxidase-like activity compared to pure Co3O4due to its large surface area and abundant active sites. The NiCo2O4possess the ability to catalyze H2O2to generate large amounts of •O2-, which can be used for bacteriostatic applications. In particular, the antibacterial system combining the spiky NiCo2O4particles and a low concentration of H2O2(100μM) exhibits an excellent bacteriostatic efficiency against bothEscherichia coli(94.44%) andStaphylococcus aureus(93.45%).
期刊介绍:
The journal aims to publish papers at the forefront of nanoscale science and technology and especially those of an interdisciplinary nature. Here, nanotechnology is taken to include the ability to individually address, control, and modify structures, materials and devices with nanometre precision, and the synthesis of such structures into systems of micro- and macroscopic dimensions such as MEMS based devices. It encompasses the understanding of the fundamental physics, chemistry, biology and technology of nanometre-scale objects and how such objects can be used in the areas of computation, sensors, nanostructured materials and nano-biotechnology.