Nails and skin co-infection by Fusarium verticillioides and Proteus vulgaris secondary to arterial occlusion of lower extremity

IF 1.5 4区生物学 Q4 MYCOLOGY

Revista Iberoamericana De Micologia Pub Date : 2024-04-01 DOI:10.1016/j.riam.2021.07.003

Yahui Feng , Zhiya Yang , Dengli Li , Juanjuan Li , Dongmei Li , Sybren de Hoog , Dongmei Shi

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引用次数: 0

Abstract

Background

Post-traumatic Fusarium infection is rare. Arterial occlusive disease, a common vascular disorder in the elderly, often leads to ischemic necrosis of the lower extremities, which in turn increases the likelihood of secondary infections. Those secondary infections can be caused by bacteria, virus, or fungi.

Case report

We present the case of a 64-year-old male patient with a co-infection by Fusarium verticillioides and Proteus vulgaris on nails and foot skin, secondary to senile arterial occlusion on the lower extremities. The skin and nails recovered well after following stent implantation and a combination treatment of itraconazole and a macrolide antibiotic. A retrospective analysis of the literature identified 17 patients with Fusarium infection, all of whom were immunocompetent.

Conclusions

Trauma may be a predisposing cause of Fusarium infection. Combination of oral itraconazole and terbinafine, or amphotericin B and surgical means, are all effective treatments.

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下肢动脉闭塞继发的黄萎病镰刀菌和寻常变形杆菌并发指甲和皮肤感染。

背景：创伤后镰刀菌感染是罕见的。动脉闭塞性疾病是老年人常见的血管疾病，常导致下肢缺血性坏死，进而增加继发感染的可能性。这些继发性感染可能由细菌、病毒或真菌引起。病例报告：我们报告一例64岁男性患者，指甲和足部皮肤同时感染黄斑镰刀菌和寻常变形杆菌，继发于下肢老年性动脉闭塞。皮肤和指甲在支架植入和伊曲康唑和大环内酯类抗生素联合治疗后恢复良好。回顾性分析文献发现17例镰孢菌感染患者，所有患者均具有免疫功能。结论：外伤可能是镰刀菌感染的易感原因。口服伊曲康唑联合特比萘芬或两性霉素B联合手术治疗均是有效的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Iberoamericana De Micologia MYCOLOGY-

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

81 days

期刊介绍： Revista Iberoamericana de Micología (Ibero-American Journal of Mycology) is the official journal of the Asociación Española de Micología, Asociación Venezolana de Micología and Asociación Argentina de Micología (The Spanish, Venezuelan, and Argentinian Mycology Associations). The Journal gives priority to publishing articles on studies associated with fungi and their pathogenic action on humans and animals, as well as any scientific studies on any aspect of mycology. The Journal also publishes, in Spanish and in English, original articles, reviews, mycology forums, editorials, special articles, notes, and letters to the editor, that have previously gone through a scientific peer review process.