DETERMINING A DIAGNOSTIC DOSE OF PIRIMIPHOS-METHYL FOR AEDES AEGYPTI USING TREATED BOTTLES1.

IF 0.9 4区农林科学 Q3 ENTOMOLOGY

Journal of the American Mosquito Control Association Pub Date : 2024-12-01 DOI:10.2987/24-7182

Gabriela González-Olvera, Rita L Vizcaino-Cabarrus, Alicia Méndez-Manzanero, Anuar Medina-Barreiro, Azael Che-Mendoza, Oscar David-Kirstein, Gonzalo Vazquez-Prokopec, Audrey E Lenhart, Pablo Manrique-Saide

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引用次数: 0

Abstract

There is a pressing need for innovative strategies to control arboviruses transmitted by Aedes aegypti. The modification of indoor residual spraying to target Ae. aegypti is one such strategy. A clinical trial quantifying the epidemiologic impact of targeted indoor residual spraying for Ae. aegypti control used a product with pirimiphos-methyl as the active ingredient in the city of Mérida, Mexico. To monitor the susceptibility of local Ae. aegypti populations over the course of the trial, we calculated a diagnostic dose for pirimiphos-methyl using the Centers for Disease Control and Prevention bottle assay. Two independent laboratories tested a series of 8 concentrations of pirimiphos-methyl, eliciting a range of mortality between 0% and 100% in an insecticide-susceptible reference strain of Ae. aegypti. The results suggested a diagnostic dose of 25 μg/ml at a diagnostic time of 30 min. This diagnostic dose of pirimiphos-methyl was used to monitor pirimphos-methyl susceptibility in Ae. aegypti throughout the trial.

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用处理过的药瓶测定甲基吡虫磷对埃及伊蚊的诊断剂量。

迫切需要创新战略来控制由埃及伊蚊传播的虫媒病毒。室内残留喷洒针对Ae的改进。埃及伊蚊就是这样一种策略。定量室内定向滞留喷洒对伊蚊流行病学影响的临床试验。在墨西哥的msamrida市，埃及伊蚊控制使用了一种含有甲基吡虫磷作为有效成分的产品。监测当地伊蚊的药敏情况。在试验过程中，我们使用疾病控制和预防中心的瓶子测定法计算了甲基吡咪磷的诊断剂量。两个独立实验室测试了一系列8种浓度的甲基吡虫磷，在一种对杀虫剂敏感的伊蚊参考菌株中，死亡率在0%至100%之间。蚊。结果提示，诊断剂量为25 μg/ml，诊断时间为30 min。埃及伊蚊在整个审判中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the American Mosquito Control Association 生物-昆虫学

CiteScore

2.10

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of the American Mosquito Control Association (JAMCA) encourages the submission of previously unpublished manuscripts contributing to the advancement of knowledge of mosquitoes and other arthropod vectors. The Journal encourages submission of a wide range of scientific studies that include all aspects of biology, ecology, systematics, and integrated pest management. Manuscripts exceeding normal length (e. g., monographs) may be accepted for publication as a supplement to the regular issue.