Global Longitudinal Strain is a Predictor of Mortality in Patients with Cardiogenic Shock.

IF 6.7 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

European Heart Journal - Cardiovascular Imaging Pub Date : 2024-12-07 DOI:10.1093/ehjci/jeae316

Kristoffer Berg-Hansen, Saki Ito, Jae Oh, Jeong Hoon Yang, Henrik Wiggers, Jacob C Jentzer

{"title":"Global Longitudinal Strain is a Predictor of Mortality in Patients with Cardiogenic Shock.","authors":"Kristoffer Berg-Hansen, Saki Ito, Jae Oh, Jeong Hoon Yang, Henrik Wiggers, Jacob C Jentzer","doi":"10.1093/ehjci/jeae316","DOIUrl":null,"url":null,"abstract":"Aims: Cardiogenic shock (CS) is a critical manifestation of severe cardiac dysfunction, necessitating precise evaluation of left ventricular function by transthoracic echocardiography. The prognostic value of global longitudinal strain (GLS) has not been examined in patients with CS. Therefore, we aimed to assess the prognostic significance of GLS in patients with CS.Methods and results: This was a retrospective study of patients with CS from 2007 to 2018 who had a transthoracic echocardiography performed within 24 hours of admission. GLS was measured and conventional parameters were obtained. Left ventricular dysfunction was categorized by GLS: >9.7% (Quartile 1), 7.0%<GLS≤9.7% (Quartile 2), 5.0%<GLS≤7.0% (Quartile 3), and ≤5.0% (Quartile 4). Outcomes included in-hospital and 1-year all-cause mortality. Among 623 CS patients with median LVEF of 31% (IQR: 24% to 41%) and median GLS of 7.0% (IQR: 5.0% to 9.7%), in-hospital mortality was 29%. Mortality increased across GLS quartiles: Quartile 1: 17%; Quartile 2: 22%; Quartile 3: 35%; and Quartile 4: 42%. GLS remained the only independent echocardiographic predictor of in-hospital mortality after adjusting for clinical covariates (adjusted odds ratio: 1.23 per 1% decrease, 95%CI: 1.04 to 1.46, P=0.015). GLS independently predicted 1-year all-cause mortality (P<0.001). The prognostic value of GLS was superior in acute coronary syndrome cases. A classification and regression tree analysis identified GLS as the most important echocardiographic variable for predicting in-hospital mortality.Conclusion: GLS independently predicted short- and long-term mortality in CS patients, surpassing conventional echocardiographic parameters in prognostic value, supporting its potential role in risk stratification in this population.","PeriodicalId":12026,"journal":{"name":"European Heart Journal - Cardiovascular Imaging","volume":" ","pages":""},"PeriodicalIF":6.7000,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Heart Journal - Cardiovascular Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ehjci/jeae316","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: Cardiogenic shock (CS) is a critical manifestation of severe cardiac dysfunction, necessitating precise evaluation of left ventricular function by transthoracic echocardiography. The prognostic value of global longitudinal strain (GLS) has not been examined in patients with CS. Therefore, we aimed to assess the prognostic significance of GLS in patients with CS.

Methods and results: This was a retrospective study of patients with CS from 2007 to 2018 who had a transthoracic echocardiography performed within 24 hours of admission. GLS was measured and conventional parameters were obtained. Left ventricular dysfunction was categorized by GLS: >9.7% (Quartile 1), 7.0%

Conclusion: GLS independently predicted short- and long-term mortality in CS patients, surpassing conventional echocardiographic parameters in prognostic value, supporting its potential role in risk stratification in this population.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

European Heart Journal - Cardiovascular Imaging CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

11.60

自引率

9.70%

发文量

708

审稿时长

4-8 weeks

期刊介绍： European Heart Journal – Cardiovascular Imaging is a monthly international peer reviewed journal dealing with Cardiovascular Imaging. It is an official publication of the European Association of Cardiovascular Imaging, a branch of the European Society of Cardiology. The journal aims to publish the highest quality material, both scientific and clinical from all areas of cardiovascular imaging including echocardiography, magnetic resonance, computed tomography, nuclear and invasive imaging. A range of article types will be considered, including original research, reviews, editorials, image focus, letters and recommendation papers from relevant groups of the European Society of Cardiology. In addition it provides a forum for the exchange of information on all aspects of cardiovascular imaging.