Recent Advances in Diphenylmethanone Oxime Reagent Chemistry for Unsaturated Bond Bifunctionalization via Energy Transfer Catalysis

IF 2.5 3区 化学 Q2 CHEMISTRY, ORGANIC
Xue-Ling Luo, Di-Jing Luo, Lu-Lu Qin, Zhi-Peng Ye, Peng-Ju Xia
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引用次数: 0

Abstract

The concurrent installation of C-X (C, O, S, N) and C-N bonds across unsaturated bond skeletons is an effective strategy for the preparation of ubiquitous motifs in pharmaceuticals and bioactive compounds. In recent years, the rapid development of bifunctionalization reactions has resulted in the emergence of bifunctional reagents as a research hotspot in this field. Among these, diphenylmethanone oxime reagents with highly active N-O bonds featuring low dissociation energy have significantly advanced the research of bifunctionalization. These reagents possess special features to simultaneously form two chemical bonds or introduce two functional groups, which not only streamlines synthetic pathways but also enhances synthetic efficiency, displaying an excellent atom- and step-economy. In addition, diphenylmethanone oxime reagents have been extensively employed in organic synthesis, attributed to their ability to facilitate the construction of complex organic structures and to provide innovative reaction pathways. In this review, we present a comprehensive overview of various diphenylmethanone oxime reagents and their applications in the bifunctional modification of unsaturated bonds through visible-light-mediated triplet–triplet energy transfer catalysis (TTEnT).
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来源期刊
CiteScore
5.40
自引率
3.60%
发文量
752
审稿时长
1 months
期刊介绍: The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.
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