Intraindividual Variability in Serial Lipoprotein(a) Concentrations Among Placebo-Treated Patients in the OCEAN(a)-DOSE Trial

IF 21.7 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of the American College of Cardiology Pub Date : 2024-12-11 DOI:10.1016/j.jacc.2024.10.081

Prakriti Gaba, Robert S. Rosenson, J. Antonio G. López, Gerald F. Watts, Thorsten M. Leucker, Julia F. Kuder, KyungAh Im, Helina Kassahun, Huei Wang, You Wu, Jingying Wang, E. Magnus Ohman, Marc S. Sabatine, Michelle L. O’Donoghue

引用次数: 0

Abstract

Lipoprotein(a) [Lp(a)] is a presumed risk factor for atherosclerotic cardiovascular disease (ASCVD), and its levels are primarily genetically determined (∼70%-90%).¹^,² As such, many guidelines and consensus groups recommend measuring Lp(a) levels only once in a person’s lifetime for risk stratification.³^,⁴ However, data assessing the intraindividual variability of Lp(a) levels over time are limited.5, 6, 7

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来源期刊

Journal of the American College of Cardiology 医学-心血管系统

CiteScore

42.70

自引率

3.30%

发文量

5097

审稿时长

2-4 weeks

期刊介绍： The Journal of the American College of Cardiology (JACC) publishes peer-reviewed articles highlighting all aspects of cardiovascular disease, including original clinical studies, experimental investigations with clear clinical relevance, state-of-the-art papers and viewpoints. Content Profile: -Original Investigations -JACC State-of-the-Art Reviews -JACC Review Topics of the Week -Guidelines & Clinical Documents -JACC Guideline Comparisons -JACC Scientific Expert Panels -Cardiovascular Medicine & Society -Editorial Comments (accompanying every Original Investigation) -Research Letters -Fellows-in-Training/Early Career Professional Pages -Editor’s Pages from the Editor-in-Chief or other invited thought leaders