Diagnosis of ccRCC

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2024-12-11 DOI:10.1038/s41585-024-00988-3

Isobel Leake

引用次数: 0

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ccRCC的诊断

透明细胞肾细胞癌（ccRCC）的诊断具有挑战性，特别是[18F]FDG PET-CT不被常规推荐。新型单域抗体（sdAb）示踪剂具有体积小、靶标识别能力强的特点，可用于肿瘤成像。在《核医学杂志》（Journal of Nuclear Medicine）上发表的一项研究的第一部分中，Zhou等人分析了CD70在肾细胞癌和正常肾组织中的表达，考虑到其作为诊断和治疗靶点的潜力。正常肾组织不表达CD70， ccRCC中CD70的表达明显高于乳头状RCC (P <；0.001)和疏色性RCC (P <；0.001)。值得注意的是，CD70的表达不受肿瘤分化或转移状态的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.