The health and economic burden of rare endocrine disease: Often ignored, always important.

IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Luna Liu, Yingzhou Shi, Yuchen Li, Wanhong Wu, Yang Tian, Xiude Fan, Chao Xu
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引用次数: 0

Abstract

Background: Rare endocrine diseases (RED) often pose chronic and life-threatening challenges, yet their economic costs and societal impact remains have not been precisely quantified.

Methods: We obtained patient data from the 2018 Nationwide Inpatient Sample (NIS) and the Nationwide Readmissions Database (NRD), identifying RED patients through International Classification of Diseases, 10th revision codes. The difference of economic burden between RED patients and the control group, including hospital length of stay, hospitalisation costs, and readmission rates, was assessed using chi-square tests.

Results: We extracted 638 083 (2.98%) RED-related records from the NIS database. Compared to patients with common conditions, RED patients showed an exceedingly high burden of disease, including significantly extended hospital stays (P < 0.05), elevated total charges (P < 0.05), and heightened mortality rates (P < 0.05). They also had a substantially increased 30-day all-cause readmission rate based on the NRD database (P < 0.05). Although the different subgroups of RED patients had varying patterns of health care utilisation and economic burdens, they all surpassed those of patients with common conditions.

Conclusions: There is a need for novel strategies aimed at mitigating the substantial RED-related burdens borne by individuals, families, and society in general, as well as funding for research and clinical trials.

罕见内分泌疾病的健康和经济负担:经常被忽视,但总是很重要。
背景:罕见内分泌疾病(RED)往往造成慢性和危及生命的挑战,但其经济成本和社会影响仍未得到精确量化。方法:我们从2018年全国住院患者样本(NIS)和全国再入院数据库(NRD)中获取患者数据,通过国际疾病分类第10次修订代码识别RED患者。RED患者与对照组之间的经济负担差异,包括住院时间、住院费用和再入院率,采用卡方检验进行评估。结果:从NIS数据库中提取red相关记录638 083条(2.98%)。与普通疾病患者相比,RED患者表现出极高的疾病负担,包括住院时间显着延长(P结论:需要新的策略,旨在减轻个人、家庭和社会普遍承担的大量RED相关负担,并为研究和临床试验提供资金。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Global Health
Journal of Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -
CiteScore
6.10
自引率
2.80%
发文量
240
审稿时长
6 weeks
期刊介绍: Journal of Global Health is a peer-reviewed journal published by the Edinburgh University Global Health Society, a not-for-profit organization registered in the UK. We publish editorials, news, viewpoints, original research and review articles in two issues per year.
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