The Association Between Frailty and Depression of Older Adults with Cancer in China: The Mediating Effect of Social Support.

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Clinical Interventions in Aging Pub Date : 2024-12-05 eCollection Date: 2024-01-01 DOI:10.2147/CIA.S487602

Nannan Jiang, Yichen Su, Yanli Zhang

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引用次数: 0

Abstract

Purpose: This study aimed to explore the mediating role of social support between depression and frailty in older adults with cancer and the regulatory role of the income level.

Patients and methods: A convenient sampling method was used to select 448 older adults with cancer from the cancer-related departments of 3 hospitals in Bengbu City, Anhui Province, China. The sociodemographic and disease-related data were collected and examined using the frailty phenotype scale, social support scale, and older adults depression scale. We examined the mediating effects using Models 4 and 59 in the SPSS PROCESS 3.5 macro program.

Results: Depression was negatively correlated with social support and its various dimensions (P < 0.05, r = -0.249 to -0.100). Frailty was positively associated with depression (P < 0.01, r = 0.388). The frailty was negatively correlated with the total score of social support and objective support (P< 0.01, r= = -0.232 to -0.182). Social support partially mediated depression and frailty, with the mediating effect accounting for 15.74% of the total development. The income level regulated only the first stage path in the mediating model (B = -0.227, P<0.001), and the mediating effect of the income level displayed individual differences.

Conclusion: The frailty of older adults with cancer is associated with depression and social support. A good level of social support can alleviate depression and reduce the risk of frailty, while a low level of social support may exacerbate the vicious cycle between depression and frailty, with income levels playing a regulatory role in this process.

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中国老年癌症患者虚弱与抑郁的关系：社会支持的中介作用。

目的：探讨社会支持在老年癌症患者抑郁与虚弱之间的中介作用以及收入水平的调节作用。患者和方法：采用方便抽样的方法，从安徽省蚌埠市3家医院癌症相关科室抽取448例老年癌症患者。收集社会人口学和疾病相关数据，并使用脆弱表型量表、社会支持量表和老年人抑郁量表进行检查。我们使用SPSS PROCESS 3.5宏程序中的模型4和模型59检验中介效应。结果：抑郁与社会支持及其各维度呈负相关（P < 0.05, r = -0.249 ~ -0.100）。虚弱与抑郁呈正相关（P < 0.01, r = 0.388）。脆弱程度与社会支持总分、客观支持总分呈负相关（P< 0.01, r= = -0.232 ~ -0.182）。社会支持对抑郁和脆弱有部分中介作用，中介效应占总发展的15.74%。收入水平在中介模型中仅调节第一阶段路径（B = -0.227, p）。结论：老年癌症患者的脆弱性与抑郁和社会支持相关。良好的社会支持水平可以缓解抑郁，降低脆弱风险，而低的社会支持水平可能加剧抑郁与脆弱的恶性循环，收入水平在这一过程中起着调节作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Interventions in Aging GERIATRICS & GERONTOLOGY-

CiteScore

6.80

自引率

2.80%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Clinical Interventions in Aging, is an online, peer reviewed, open access journal focusing on concise rapid reporting of original research and reviews in aging. Special attention will be given to papers reporting on actual or potential clinical applications leading to improved prevention or treatment of disease or a greater understanding of pathological processes that result from maladaptive changes in the body associated with aging. This journal is directed at a wide array of scientists, engineers, pharmacists, pharmacologists and clinical specialists wishing to maintain an up to date knowledge of this exciting and emerging field.