{"title":"Neutrophil extracellular traps worsen clotting and neuroinflammation in cavernomas","authors":"","doi":"10.1038/s44161-024-00584-z","DOIUrl":null,"url":null,"abstract":"Cerebral cavernous malformations (CCMs) can cause strokes and hemorrhages. A study reveals that blocking the formation of neutrophil extracellular traps (NETs) reduces CCM lesions and the associated clots and neuroinflammation, which suggests that targeting NETs might pave the way for new therapies to manage CCMs.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"3 12","pages":"1385-1386"},"PeriodicalIF":9.4000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00584-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Cerebral cavernous malformations (CCMs) can cause strokes and hemorrhages. A study reveals that blocking the formation of neutrophil extracellular traps (NETs) reduces CCM lesions and the associated clots and neuroinflammation, which suggests that targeting NETs might pave the way for new therapies to manage CCMs.
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