Retention in care among people living with human immunodeficiency virus (HIV) in a low-resource setting.

IF 1.4 4区医学 Q4 IMMUNOLOGY

International Journal of STD & AIDS Pub Date : 2025-03-01 Epub Date: 2024-12-10 DOI:10.1177/09564624241306152

Ahmed Cordie, Rahma Mohamed, Ammar Hatem, Mahmoud Essam, Shaker Wagih Shaltout, Naeema El Garhy, Lamiaa Al Sehemy, Mirella Sherif, Reham Awad Awad, Mariam Ismail Abdelraouf, Aya M Al-Sharif, Ahmed Ramadan, Sahar Hassany, Engy El Khateeb, Amal M Sayed, Zainab Wafik Zakaria Masoud, Rania Soliman Hamza, Hend Hamed Tamim, Mona Salah Eldin Hamdy, Gamal Esmat, Haidi Karam-Allah Ramadan

{"title":"Retention in care among people living with human immunodeficiency virus (HIV) in a low-resource setting.","authors":"Ahmed Cordie, Rahma Mohamed, Ammar Hatem, Mahmoud Essam, Shaker Wagih Shaltout, Naeema El Garhy, Lamiaa Al Sehemy, Mirella Sherif, Reham Awad Awad, Mariam Ismail Abdelraouf, Aya M Al-Sharif, Ahmed Ramadan, Sahar Hassany, Engy El Khateeb, Amal M Sayed, Zainab Wafik Zakaria Masoud, Rania Soliman Hamza, Hend Hamed Tamim, Mona Salah Eldin Hamdy, Gamal Esmat, Haidi Karam-Allah Ramadan","doi":"10.1177/09564624241306152","DOIUrl":null,"url":null,"abstract":"Background: This study aimed to evaluate the retention in care among a cohort of Egyptian people living with HIV (PLWHIV).Method: The study was conducted on PLWHIV attending Kasr Alainy HIV and Viral Hepatitis Centre, Cairo, Egypt, from January 1, 2019, to March 31, 2023. PLWHIV were considered not retained in care if there was no documented clinical visit or HIV viral load (VL) or CD4 count test for more than 6 months from their last recorded visit or test. Multivariable logistic regression analysis was used to test factors associated with retention in care.Results: After excluding those who died and were referred, 369 PLWHIV were included in the analysis, and retention in care was observed in 325 (88%). The majority were males (81.8%) with a median age of 34 [29-41] years. Undetectable VL (OR: 3.555; 95% CI: 1.49-8.47), hepatitis B vaccination (OR: 2.835; 95% CI: 1.07-7.48), CD4 test availability (OR: 2.604; 95% CI: 1.02-6.64), receiving dolutegravir based antiretroviral therapy (OR: 2.429; 95% CI: 1.06-5.537), and longer duration of know HIV infection (OR: 1.025; 95% CI: 1.01- 1.04) were correlated with retention in care. Surprisingly, higher education levels were negatively correlated with retention in care (OR: 0.195, 95%: CI: 0.071-0.533), suggesting the need for further research to explore this relationship.Conclusion: These results are invaluable for developing targeted interventions and informing health policies to improve retention in HIV care in Egypt. Enhancing access to VL and CD4 testing, promoting VL suppression, and focusing on specific groups at risk of dropping out of care are essential strategies.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"275-282"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of STD & AIDS","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/09564624241306152","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/10 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: This study aimed to evaluate the retention in care among a cohort of Egyptian people living with HIV (PLWHIV).

Method: The study was conducted on PLWHIV attending Kasr Alainy HIV and Viral Hepatitis Centre, Cairo, Egypt, from January 1, 2019, to March 31, 2023. PLWHIV were considered not retained in care if there was no documented clinical visit or HIV viral load (VL) or CD4 count test for more than 6 months from their last recorded visit or test. Multivariable logistic regression analysis was used to test factors associated with retention in care.

Results: After excluding those who died and were referred, 369 PLWHIV were included in the analysis, and retention in care was observed in 325 (88%). The majority were males (81.8%) with a median age of 34 [29-41] years. Undetectable VL (OR: 3.555; 95% CI: 1.49-8.47), hepatitis B vaccination (OR: 2.835; 95% CI: 1.07-7.48), CD4 test availability (OR: 2.604; 95% CI: 1.02-6.64), receiving dolutegravir based antiretroviral therapy (OR: 2.429; 95% CI: 1.06-5.537), and longer duration of know HIV infection (OR: 1.025; 95% CI: 1.01- 1.04) were correlated with retention in care. Surprisingly, higher education levels were negatively correlated with retention in care (OR: 0.195, 95%: CI: 0.071-0.533), suggesting the need for further research to explore this relationship.

Conclusion: These results are invaluable for developing targeted interventions and informing health policies to improve retention in HIV care in Egypt. Enhancing access to VL and CD4 testing, promoting VL suppression, and focusing on specific groups at risk of dropping out of care are essential strategies.

查看原文本刊更多论文

在资源匮乏的环境中，人类免疫缺陷病毒（HIV）感染者继续接受护理。

背景：本研究旨在评估埃及艾滋病毒感染者（PLWHIV）队列中的护理保留情况。方法：研究对象为2019年1月1日至2023年3月31日在埃及开罗Kasr Alainy HIV和病毒性肝炎中心就诊的plwhv患者。如果从最后一次就诊或检测记录起超过6个月没有记录的临床就诊或HIV病毒载量（VL）或CD4计数检测，则认为plhiv未保留在护理中。采用多变量logistic回归分析检验与留置护理相关的因素。结果：在排除死亡和转介后，369例PLWHIV纳入分析，其中325例（88%）保留护理。男性居多（81.8%），中位年龄34岁[29-41]。检测不到VL (OR: 3.555；95% CI: 1.49-8.47)，乙肝疫苗接种(OR: 2.835；95% CI: 1.07-7.48)， CD4检测可用性(OR: 2.604；95% CI: 1.02-6.64)，接受以多替格拉韦为基础的抗逆转录病毒治疗(OR: 2.429；95% CI: 1.06-5.537)，已知HIV感染持续时间较长(OR: 1.025；95% CI: 1.01- 1.04)与护理留置相关。令人惊讶的是，高等教育水平与护理保留率呈负相关（OR: 0.195, 95%: CI: 0.071-0.533），这表明需要进一步研究来探索这种关系。结论：这些结果对于制定有针对性的干预措施和告知卫生政策以改善埃及艾滋病毒护理的保留情况具有宝贵的价值。加强VL和CD4检测的可及性，促进VL抑制，并关注有退出治疗风险的特定群体，这些都是必不可少的战略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of STD & AIDS 医学-传染病学

CiteScore

2.60

自引率

7.10%

发文量

144

审稿时长

3-6 weeks

期刊介绍： The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).