Flowsheet Testing for Separation of Lutetium-177 from an Irradiated Ytterbium Target

IF 0.9 Q4 CHEMISTRY, INORGANIC & NUCLEAR

Radiochemistry Pub Date : 2024-12-11 DOI:10.1134/S1066362224050047

E. V. Ambul, N. D. Goletskiy, A. A. Naumov, E. A. Puzikov, M. V. Mamchich, E. O. Zagladkin, N. A. Dedov, N. A. Semenova, S. A. Rodionov, N. V. Kovalev, A. M. Prokoshin, I. A. Ushakov, V. V. Zukau

引用次数: 0

Abstract

The results of an experiment to verify a complex technology for isolation of ¹⁷⁷Lu from an irradiated 1-g ytterbium target are presented. The main components of the experimental installation, which is mounted in a research hot cell, are described. These components include the extraction and separation of lutetium and ytterbium, the evaporation and preconcentration of ¹⁷⁷Lu, and its chromatographic purification. The feasibility of obtaining a pharmaceutical substance no carrier added lutetium-177 trichloride that meets the standards set by the European Pharmacopoeia has been confirmed.

Abstract Image

查看原文本刊更多论文

从辐照镱靶中分离镥-177的工艺流程试验

本文介绍了一种从辐照1g镱靶中分离177Lu的复杂技术的实验结果。介绍了安装在研究热槽内的实验装置的主要组成部分。这些组分包括镥和镱的提取分离、177Lu的蒸发预富集和色谱纯化。证实了制备符合欧洲药典标准的无载体添加三氯化镥-177的可行性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Radiochemistry CHEMISTRY, INORGANIC & NUCLEAR-

CiteScore

1.30

自引率

33.30%

发文量

期刊介绍： Radiochemistry is a journal that covers the theoretical and applied aspects of radiochemistry, including basic nuclear physical properties of radionuclides; chemistry of radioactive elements and their compounds; the occurrence and behavior of natural and artificial radionuclides in the environment; nuclear fuel cycle; radiochemical analysis methods and devices; production and isolation of radionuclides, synthesis of labeled compounds, new applications of radioactive tracers; radiochemical aspects of nuclear medicine; radiation chemistry and after-effects of nuclear transformations.