Conductive poly (vinyl alcohol)/berberine/AgNWs gellable composite film with antibacterial activity for wound dressing and acute massive hemorrhage warning

IF 23.2 2区材料科学 Q1 MATERIALS SCIENCE, COMPOSITES

Advanced Composites and Hybrid Materials Pub Date : 2024-12-11 DOI:10.1007/s42114-024-01112-0

Jiahui Lin, Mengman Weng, Yongshuang Xiao, Shengdong Liu, Qing Xiang, Hassan Algadi, Dalal A. Alshammari, Ahmed M. Fallatah, Zheng Zhao, Yonggang Min, Mohamed M. Ibrahim, Jintao Huang

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引用次数: 0

Abstract

Wound infection and acute massive hemorrhage pose a huge challenge for clinical treatment. Recently, wound dressings containing natural bioactive component have been studied to prevent infection and accelerate wound healing. However, traditional wound dressings lack coping measures to the acute wound massive hemorrhage. Herein, poly (vinyl alcohol) (PVA)/berberine (BBR)/silver nanowires (AgNWs) gellable composite film was prepared by a simple thermo-crosslinking method. The film possesses the property of transforming into gel with adhesion ability after absorbing water. The incorporation of natural BBR and the loading of AgNWs make the film achieve prominent antibacterial performance. Therefore, this gellable film with adhesion ability and antibacterial performance can be used as wound dressing. Remarkably, the combination of the conductivity of AgNWs and the water absorption capability of PVA endows the gellable film with wonderful acute massive hemorrhage warning function to promoting timely treatment. The findings also elucidate excellent mechanical property and reshape ability of the film. Consequently, the gellable film provided in this study holds significant potential in wound healing and acute massive hemorrhage warning applications.

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来源期刊

Advanced Composites and Hybrid Materials Multiple-

CiteScore

26.00

自引率

21.40%

发文量

185

期刊介绍： Advanced Composites and Hybrid Materials is a leading international journal that promotes interdisciplinary collaboration among materials scientists, engineers, chemists, biologists, and physicists working on composites, including nanocomposites. Our aim is to facilitate rapid scientific communication in this field. The journal publishes high-quality research on various aspects of composite materials, including materials design, surface and interface science/engineering, manufacturing, structure control, property design, device fabrication, and other applications. We also welcome simulation and modeling studies that are relevant to composites. Additionally, papers focusing on the relationship between fillers and the matrix are of particular interest. Our scope includes polymer, metal, and ceramic matrices, with a special emphasis on reviews and meta-analyses related to materials selection. We cover a wide range of topics, including transport properties, strategies for controlling interfaces and composition distribution, bottom-up assembly of nanocomposites, highly porous and high-density composites, electronic structure design, materials synergisms, and thermoelectric materials. Advanced Composites and Hybrid Materials follows a rigorous single-blind peer-review process to ensure the quality and integrity of the published work.