Muriel Gauthier , Nicolas-Charles Roche , Thomas Audoual , Philippe Aldebert , Pierre-Laurent Massoure
{"title":"Une dyspnée révélant un syndrome de platypnée-orthodéoxie chez une patiente insuffisante cardiaque","authors":"Muriel Gauthier , Nicolas-Charles Roche , Thomas Audoual , Philippe Aldebert , Pierre-Laurent Massoure","doi":"10.1016/j.revmed.2024.11.013","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>The platypnea orthodeoxia syndrome is a rare clinical entity combining positional dyspnea and arterial oxygen desaturation during the transition to orthostatism, reversible on return to decubitus. The most frequent etiology of this syndrome is the presence of a patent foramen ovale (PFO) responsible for a right-to-left intracardiac shunt, the severity of which results in significant functional disability and a risk of death from hypoxia.</div></div><div><h3>Case report</h3><div>We report the case of a 93-year old patient on long-term oxygen, initially hospitalized for acute heart failure following a community-acquired urinary tract infection. The onset of recurrent positional dyspnea with desaturation on raising revealed a platypnea orthodeoxia syndrome. Transesophageal echocardiogram with bubble test revealed a large right-to-left shunt through a PFO, percutaneous closure of which led to complete resolution of symptoms and discontinuation of oxygen therapy.</div></div><div><h3>Discussion and conclusion</h3><div>The platypnea orthodeoxia syndrome associated with a patent foramen ovale often suffers from delayed diagnosis. Advanced age and co-morbidities should not prevent patients from undergoing percutaneous PFO closure, as the clinical benefit is important.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 2","pages":"Pages 116-119"},"PeriodicalIF":0.7000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue De Medecine Interne","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0248866324013110","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
The platypnea orthodeoxia syndrome is a rare clinical entity combining positional dyspnea and arterial oxygen desaturation during the transition to orthostatism, reversible on return to decubitus. The most frequent etiology of this syndrome is the presence of a patent foramen ovale (PFO) responsible for a right-to-left intracardiac shunt, the severity of which results in significant functional disability and a risk of death from hypoxia.
Case report
We report the case of a 93-year old patient on long-term oxygen, initially hospitalized for acute heart failure following a community-acquired urinary tract infection. The onset of recurrent positional dyspnea with desaturation on raising revealed a platypnea orthodeoxia syndrome. Transesophageal echocardiogram with bubble test revealed a large right-to-left shunt through a PFO, percutaneous closure of which led to complete resolution of symptoms and discontinuation of oxygen therapy.
Discussion and conclusion
The platypnea orthodeoxia syndrome associated with a patent foramen ovale often suffers from delayed diagnosis. Advanced age and co-morbidities should not prevent patients from undergoing percutaneous PFO closure, as the clinical benefit is important.
期刊介绍:
Official journal of the SNFMI, La revue de medecine interne is indexed in the most prestigious databases. It is the most efficient French language journal available for internal medicine specialists who want to expand their knowledge and skills beyond their own discipline. It is also the main French language international medium for French research works. The journal publishes each month editorials, original articles, review articles, short communications, etc. These articles address the fundamental and innumerable facets of internal medicine, spanning all medical specialties. Manuscripts may be submitted in French or in English.
La revue de medecine interne also includes additional issues publishing the proceedings of the two annual French meetings of internal medicine (June and December), as well as thematic issues.